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(Circulation. 1952;6:538.)
© 1952 American Heart Association, Inc.

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The Clinical Significance of Postextrasystolic T-Wave Changes

HAROLD D. LEVINE M.D.¹; BERNARD LOWN M.D.¹; RICHARD B. STREEPER M.D.¹

¹ From the Medical Clinic of the Peter Bent Brigham Hospital and the Department of Medicine, Harvard Medical School, Boston, and the Heart Disease Epidemiology Study, National Heart Institute.

Examination of the T wave of the beat following the pause occurring in many conditions, notably premature systoles, may show variations from the regular T waves in the same lead without concomitant change in the QRS complex. This phenomenon, when pronounced, is generally associated with evidence of myocardial impairment and is correlated with abnormal reaction to stress tests for coronary insufficiency. Inquiry is here made into the factors affecting this phenomenon, its mechanism topography, persistency and clinical significance.

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