Circulation, Vol 60, 22-25, Copyright © 1979 by American Heart Association
S Heyden, G Heiss, C Manegold, HA Tyroler, CG Hames, AG Bartel and G Cooper
Conflicting reports on the effect of smoking and coffee drinking on
lipoproteins prompted us to study the combined effect of these two
associated, widely prevalent habits in 361 persons randomly sampled from
the Evans County cohort. Low-density lipoprotein (LDL) cholesterol levels
were significantly higher among persons who smoked cigarettes and consumed
five or more cups of coffee per day than among nonsmokers who abstained
from coffee. Conversely, high-density lipoprotein (HDL) cholesterol was
higher in persons who did not smoke or drink coffee than in
coffee-consuming smokers. However, this trend was not statistically
significant. Triglycerides and very low-density lipoprotein (VLDL)
cholesterol were highest among smokers who drank five or more cups of
coffee per day, but these differences did not reach statistical
significance. Lipoprotein cholesterol levels were adjusted for age, sex and
body mass. Smoking and coffee drinking interact in affecting LDL and total
cholesterol, but coffee drinking alone did not appear to affect blood
lipids.
ARTICLES
The combined effect of smoking and coffee drinking on LDL and HDL cholesterol
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