Assessment of left ventricular ejection fraction and volumes by real- time, two-dimensional echocardiography. A comparison of cineangiographic and radionuclide techniques

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Circulation. 1979;60:760-766

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Assessment of left ventricular ejection fraction and volumes by real- time, two-dimensional echocardiography. A comparison of cineangiographic and radionuclide techniques

ED Folland, AF Parisi, PF Moynihan, DR Jones, CL Feldman and DE Tow

Five different algorithms for determining left ventricular (LV) ejection fraction (EF) and volumes from two-dimensional echocardiographic examination (TDE) were compared with standard methods for obtaining EF and volume from x-ray cineangiography (cine) and EF from radionuclide ventriculography (RVG) in 35 patients. Although all methods correlated positively, the degree of correlation varied with the algorithm used. For EF determination, TDE algorithms (especially those using multiple planes of section) were superior to unidimensional algorithms commonly used with M-mode echocardiography. The best algorithm (modified Simpson's rule) correlated well enough with cine EF (r = 0.78; SEE 0.097) and RVG EF (r = 0.75; SEE 0.087) to make clinically useful estimates. TDE volumes also correlated meaningfully with cine end-diastolic and end-systole volumes (r = 084; n = 70) but were associated with a large standard error of the estimate (43 ml) and offered less advantage over unidimensional volume estimates. Quantitative application of TDE appears to be a useful noninvasive method of evaluating LVEF, but is not as useful for estimating LV volumes.

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				M. Petretta, L. Spinelli, F. Marciano, C. Apicella, M. L. E. Vicario, G. Testa, M. Volpe, and D. Bonaduce Effects of losartan treatment on cardiac autonomic control during volume loading in patients with DCM Am J Physiol Heart Circ Physiol, July 1, 2000; 279(1): H86 - H92. [Abstract] [Full Text] [PDF]

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				E. T. Alboliras, C. Mavroudis, E. Pahl, S. S. Gidding, C. L. Backer, and A. P. Rocchini Left ventricular growth in selected hypoplastic left ventricles: outcome after repair of coarctation of aorta Ann. Thorac. Surg., August 1, 1999; 68(2): 549 - 555. [Abstract] [Full Text] [PDF]

				W.-L. Lee, J.-W. Chen, C.-T. Ting, S.-J. Lin, and P. H. Wang Changes of the Insulin-Like Growth Factor I System during Acute Myocardial Infarction: Implications on Left Ventricular Remodeling J. Clin. Endocrinol. Metab., May 1, 1999; 84(5): 1575 - 1581. [Abstract] [Full Text]

				N G Fisher and A J Marshall Management options: Anthracycline-induced cardiomyopathy Postgrad. Med. J., May 1, 1999; 75(883): 265 - 268. [Abstract] [Full Text]

				H. Schoder, R. Campisi, T. Ohtake, C. K. Hoh, D. H. Moon, J. Czernin, and H. R. Schelbert Blood flow-metabolism imaging with positron emission tomography in patients with diabetes mellitus for the assessment of reversible left ventricular contractile dysfunction J. Am. Coll. Cardiol., April 1, 1999; 33(5): 1328 - 1337. [Abstract] [Full Text] [PDF]