Circulation, Vol 60, 760-766, Copyright © 1979 by American Heart Association
ED Folland, AF Parisi, PF Moynihan, DR Jones, CL Feldman and DE Tow
Five different algorithms for determining left ventricular (LV) ejection
fraction (EF) and volumes from two-dimensional echocardiographic
examination (TDE) were compared with standard methods for obtaining EF and
volume from x-ray cineangiography (cine) and EF from radionuclide
ventriculography (RVG) in 35 patients. Although all methods correlated
positively, the degree of correlation varied with the algorithm used. For
EF determination, TDE algorithms (especially those using multiple planes of
section) were superior to unidimensional algorithms commonly used with
M-mode echocardiography. The best algorithm (modified Simpson's rule)
correlated well enough with cine EF (r = 0.78; SEE 0.097) and RVG EF (r =
0.75; SEE 0.087) to make clinically useful estimates. TDE volumes also
correlated meaningfully with cine end-diastolic and end-systole volumes (r
= 084; n = 70) but were associated with a large standard error of the
estimate (43 ml) and offered less advantage over unidimensional volume
estimates. Quantitative application of TDE appears to be a useful
noninvasive method of evaluating LVEF, but is not as useful for estimating
LV volumes.
ARTICLES
Assessment of left ventricular ejection fraction and volumes by real- time, two-dimensional echocardiography. A comparison of cineangiographic and radionuclide techniques
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