Circulation, Vol 60, 1605-1608, Copyright © 1979 by American Heart Association
RD Remington
The history of randomized, controlled, clinical trials is reviewed.
Cooperative clinical trials are reviewed and summarized, and specific needs
for future trials are identified. Improved policy on resource allocation
decisions for clinical trials vs other forms of research is necessary,
particularly as such trials begin to translate improved therapeutic
knowledge into community level disease control.
ARTICLES
Research related to validation of treatment modalities by large-scale clinical trials
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