Circulation, Vol 61, 374-380, Copyright © 1980 by American Heart Association
JA Stewart, D Silimperi, P Harris, NK Wise, TD Fraker Jr and JA Kisslo
Eighty-seven patients with the clinical syndrome of infective endocarditis
were examined by M-mode and two-dimensional echocardiography. Patients were
divided into two groups based on the presence or absence of
echocardiographically detected vegetative lesions. Group 1 consisted of 47
patients with one or more vegetations. Group 2 consisted of 40 patients
without evidence of vegetations. Group 1 patients had a higher rate of
complications: emboli, congestive heart failure and the need for surgical
intervention. Analysis of morphologic characteristics of the vegetations in
group 1 was of no predictive value for complications in individual
patients. Two-thirds of the vegetations persisted unaltered well beyond the
period of bacteriologic cure without significant complications. No
characteristic alteration of the vegetations predicted the efficacy of
medical therapy. Although the detection of vegetations by echocardiography
in patients with the clinical syndrome of endocarditis clearly identifies a
subgroup at risk for complications, decisions regarding clinical management
made solely on the basis of the presence or absence of vegetative lesions
are hazardous. Management of such patients must continue to be based on the
clinical integration of multiple factors.
ARTICLES
Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications
This article has been cited by other articles:
![]() |
D. N. Salem, P. T. O'Gara, C. Madias, and S. G. Pauker Valvular and Structural Heart Disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition) Chest, June 1, 2008; 133(6_suppl): 593S - 629S. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. N. Salem, P. D. Stein, A. Al-Ahmad, H. I. Bussey, D. Horstkotte, N. Miller, and S. G. Pauker Antithrombotic Therapy in Valvular Heart Disease--Native and Prosthetic: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest, September 1, 2004; 126(3_suppl): 457S - 482S. [Abstract] [Full Text] [PDF] |
||||
![]() |
K Greaves, D Mou, A Patel, and D S Celermajer Clinical criteria and the appropriate use of transthoracic echocardiography for the exclusion of infective endocarditis Heart, March 1, 2003; 89(3): 273 - 275. [Abstract] [Full Text] [PDF] |
||||
![]() |
I. Vilacosta, C. Graupner, J. SanRoman, C. Sarria, R. Ronderos, C. Fernandez, L. Mancini, O. Sanz, J. Sanmartin, and W. Stoermann Risk of embolization after institution of antibiotic therapy for infective endocarditis J. Am. Coll. Cardiol., May 1, 2002; 39(9): 1489 - 1495. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. M. Donlan and J. W. Costerton Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms Clin. Microbiol. Rev., April 1, 2002; 15(2): 167 - 193. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Heper and Y. Yorukoglu Clinical, Bacteriologic and Echocardiographic Evaluation of Infective Endocarditis in Ankara, Turkey Angiology, March 1, 2002; 53(2): 191 - 197. [Abstract] [PDF] |
||||
![]() |
C. Piper, R. Hetzer, R. Korfer, R. Bergemann, and D. Horstkotte The importance of secondary mitral valve involvement in primary aortic valve endocarditis. The mitral kissing vegetation Eur. Heart J., January 1, 2002; 23(1): 79 - 86. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. Mathew, A. Anand, T. Addai, and S. Freels Value of Echocardiographic Findings in Predicting Cardiovascular Complications in Infective Endocarditis Angiology, December 1, 2001; 52(12): 801 - 809. [Abstract] [PDF] |
||||
![]() |
G. Di Salvo, G. Habib, V. Pergola, J.-F. Avierinos, E. Philip, J.-P. Casalta, J.-M. Vailloud, G. Derumeaux, J. Gouvernet, P.i. Ambrosi, et al. Echocardiography predicts embolic events in infective endocarditis J. Am. Coll. Cardiol., March 15, 2001; 37(4): 1069 - 1076. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. N. Salem, D. Hartnett Daudelin, H. J. Levine, S. G. Pauker, M. H. Eckman, and J. Riff Antithrombotic Therapy in Valvular Heart Disease Chest, January 1, 2001; 119 (2009): 207S - 219S. [Full Text] [PDF] |
||||
![]() |
S J D BRECKER, J R PEPPER, and S J EYKYN Aortic root abscess Heart, September 1, 1999; 82(3): 260 - 262. [Full Text] [PDF] |
||||
![]() |
A. M. Aly, P. M. Simpson, and R. A. Humes The Role of Transthoracic Echocardiography in the Diagnosis of Infective Endocarditis in Children Arch Pediatr Adolesc Med, September 1, 1999; 153(9): 950 - 954. [Abstract] [Full Text] [PDF] |
||||
![]() |
L. I. Kupferwasser, G. Hafner, S. Mohr-Kahaly, R. Erbel, J.u. Meyer, and H. Darius The presence of infection-related antiphospholipid antibodies in infective endocarditis determines a major risk factor for embolic events J. Am. Coll. Cardiol., April 1, 1999; 33(5): 1365 - 1371. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. R. Lindner, R. A. Case, J. M. Dent, R. D. Abbott, W. M. Scheld, and S. Kaul Diagnostic Value of Echocardiography in Suspected Endocarditis : An Evaluation Based on the Pretest Probability of Disease Circulation, February 15, 1996; 93(4): 730 - 736. [Abstract] [Full Text] |
||||
![]() |
D. D. Muehrcke, B. W. Lytle, and D. M. Cosgrove III Surgical and Long-Term Antifungal Therapy for Fungal Prosthetic Valve Endocarditis Ann. Thorac. Surg., September 1, 1995; 60(3): 538 - 543. [Abstract] [Full Text] |
||||
![]() |
F. Nomura, D. J. Penny, S. Menahem, A. Pawade, and T. R. Karl Surgical Intervention for Infective Endocarditis in Infancy and Childhood Ann. Thorac. Surg., July 1, 1995; 60(1): 90 - 95. [Abstract] [Full Text] |
||||
![]() |
S. R. Hecht and M. Berger Right-sided Endocarditis in Intravenous Drug Users: Prognostic Features in 102 Episodes Ann Intern Med, October 1, 1992; 117(7): 560 - 566. [Abstract] [PDF] |
||||
![]() |
A. J. Burger, B. Peart, H. Jabi, and R. C. Touchon The Role of Two-Dimensional Echocardiography in the Diagnosis of Ineffective Endocarditis Angiology, July 1, 1991; 42(7): 552 - 560. [Abstract] [PDF] |
||||
![]() |
J. M. Steckelberg, J. G. Murphy, D. Ballard, K. Bailey, A. J. Tajik, C. P. Taliercio, E. R. Giuliani, and W. R. Wilson Emboli in Infective Endocarditis: The Prognostic Value of Echocardiography Ann Intern Med, April 15, 1991; 114(8): 635 - 640. [Abstract] [PDF] |
||||
![]() |
F. L. Porkolab, D. L. Weinbaum, D. B. Lerberg, and J. C. Phillips The Source of Recurrent Bacteremia Identified by Trans-esophageal Echocardiography Ann Intern Med, April 15, 1990; 112(8): 628 - 629. [Abstract] [PDF] |
||||
![]() |
A. S. Manolis and H. Melita Echocardiographic and Clinical Correlates in Drug Addicts With Infective Endocarditis: Implications of Vegetation Size Arch Intern Med, November 1, 1988; 148(11): 2461 - 2465. [Abstract] [PDF] |
||||
![]() |
F. Espersen, L. J. Wheat, A T. Bemis, A. White, A. S. Bayer, and D. C. Hooper Solid-Phase Radioimmunoassay for IgG Antibodies to Staphylococcus epidermidis: Use in Serious Coagulase-Negative Staphylococcal Infections Arch Intern Med, April 1, 1987; 147(4): 689 - 693. [Abstract] [PDF] |
||||
![]() |
A. S. Bayer, K. Lam, L. Ginzton, D. C. Norman, C.-Y. Chiu, and J. I. Ward Staphylococcus aureus Bacteremia: Clinical, Serologic, and Echocardiographic Findings in Patients With and Without Endocarditis Arch Intern Med, March 1, 1987; 147(3): 457 - 462. [Abstract] [PDF] |
||||
![]() |
J. T. Bricker, L. A. Latson, J. C. Huhta, and H. P. Gutgesell Echocardiographic Evaluation of Infective Endocarditis in Children Clinical Pediatrics, June 1, 1985; 24(6): 312 - 317. [Abstract] [PDF] |
||||
![]() |
M. Zabalgoitia-Reyes, D. J. Mehlman, and J. V. Talano Persistent Fever With Aortic Valve Endocarditis Arch Intern Med, February 1, 1985; 145(2): 327 - 328. [Abstract] [PDF] |
||||
![]() |
D. Wong, P. Anthony, N. Chandraratna, R. M. Wishnow, V. Dusitnanond, and A. Nimalasuriya Clinical Implications of Large Vegetations in Infectious Endocarditis Arch Intern Med, October 1, 1983; 143(10): 1874 - 1877. [Abstract] [PDF] |
||||
![]() |
R.-E. W. Kavey, D. M. Frank, C. J. Byrum, M. S. Blackman, H. M. Sondheimer, and E. L. Bove Two-dimensional Echocardiographic Assessment of Infective Endocarditis in Children Arch Pediatr Adolesc Med, September 1, 1983; 137(9): 851 - 856. [Abstract] [PDF] |
||||
![]() |
S. W. Parker, M. A. Apicella, and C. M. Fuller Hemophilus Endocarditis: Two Patients With Complications Arch Intern Med, January 1, 1983; 143(1): 48 - 51. [Abstract] [PDF] |
||||
![]() |
A. S. Bayer Staphylococcal Bacteremia and Endocarditis: State of the Art Arch Intern Med, June 1, 1982; 142(6): 1169 - 1177. [Abstract] [PDF] |
||||
![]() |
M. J. DINUBILE Surgery in Active Endocarditis Ann Intern Med, May 1, 1982; 96(5): 650 - 659. [Abstract] [PDF] |
||||
![]() |
R. L. POPP, D. S. RUBENSON, C. R. TUCKER, and J. W. FRENCH Echocardiography: M-Mode and Two-Dimensional Methods Ann Intern Med, December 1, 1980; 93(6): 844 - 856. [Abstract] [PDF] |
||||
![]() |
G. S. Mintz and M. N. Kotler Clinical Value and Limitations of Echocardiography: Its Use in the Study of Patients With Infectious Endocarditis Arch Intern Med, August 1, 1980; 140(8): 1022 - 1027. [Abstract] [PDF] |
||||
|
Circulation Home | Subscriptions | Archives | Feedback | Authors | Help | AHA Journals Home | Search Copyright © 1980 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited. |