This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Allen, W. H. Articles by Stinson, P. Search for Related Content PubMed PubMed Citation Articles by Allen, W. H. Articles by Stinson, P.

Circulation, Vol 62, 522-527, Copyright © 1980 by American Heart Association

ARTICLES

Five-year follow-up of maximal treadmill stress test in asymptomatic men and women

WH Allen, WS Aronow, P Goodman and P Stinson

A five-year follow-up of 888 asymptomatic men and women without known coronary heart disease (CHD) who had a maximal treadmill stress test (MTST) revealed a CHD incidence of 1.1% per year. In women, exercise duration of 3 minutes or less by the Ellestad protocol correlated with subsequent development of CHD (p less than 0.001), although abnormal ST- segment and R-wave responses did not. In men 40 years of age or younger, the MTST did not correlate with subsequent CHD. In men older than 40 years, ischemic ST response (p less than 0.01), an increase or no change in R wave (p less than 0.01), and an exercise duration of 5 minutes of less (p less than 0.001) all correlated with subsequent development of CHD. Five of five men (100%) who had all three criteria developed CHD within 5 years. When men older than 40 years who had all three criteria either present or absent were considered, specificity was 100%. The sensitivity, specificity, predictive value of an abnormal test, and risk ratio for developing CHD within 5 years for the various MTST criteria alone and in combination are tabulated.

This article has been cited by other articles:

				S. Mora, R. F. Redberg, A. R. Sharrett, and R. S. Blumenthal Enhanced Risk Assessment in Asymptomatic Individuals With Exercise Testing and Framingham Risk Scores Circulation, September 13, 2005; 112(11): 1566 - 1572. [Abstract] [Full Text] [PDF]

				G. Erikssen, J. Bodegard, J. V. Bjornholt, K. Liestol, D. S. Thelle, and J. Erikssen Exercise testing of healthy men in a new perspective: from diagnosis to prognosis Eur. Heart J., June 1, 2004; 25(11): 978 - 986. [Abstract] [Full Text] [PDF]

				A. Fowler-Brown, M. Pignone, M. Pletcher, J. A. Tice, S. F. Sutton, and K. N. Lohr Exercise Tolerance Testing To Screen for Coronary Heart Disease: A Systematic Review for the Technical Support for the U.S. Preventive Services Task Force Ann Intern Med, March 1, 2004; (2004) 6052004040601. [Abstract] [Full Text]

				S. Mora, R. F. Redberg, Y. Cui, M. K. Whiteman, J. A. Flaws, A. R. Sharrett, and R. S. Blumenthal Ability of Exercise Testing to Predict Cardiovascular and All-Cause Death in Asymptomatic Women: A 20-Year Follow-up of the Lipid Research Clinics Prevalence Study JAMA, September 24, 2003; 290(12): 1600 - 1607. [Abstract] [Full Text] [PDF]

				T. M. Rywik, F. C. O'Connor, N. S. Gittings, J. G. Wright, A. A. Khan, and J. L. Fleg Role of Nondiagnostic Exercise-Induced ST-Segment Abnormalities in Predicting Future Coronary Events in Asymptomatic Volunteers Circulation, November 26, 2002; 106(22): 2787 - 2792. [Abstract] [Full Text] [PDF]

				G. F. Fletcher, G. J. Balady, E. A. Amsterdam, B. Chaitman, R. Eckel, J. Fleg, V. F. Froelicher, A. S. Leon, I. L. Pina, R. Rodney, et al. Exercise Standards for Testing and Training: A Statement for Healthcare Professionals From the American Heart Association Circulation, October 2, 2001; 104(14): 1694 - 1740. [Full Text] [PDF]

				P. C. Deedwania Silent ischemia predicts poor outcome in high-risk healthy men J. Am. Coll. Cardiol., July 1, 2001; 38(1): 80 - 83. [Full Text] [PDF]

				B. J. Maron, C. G. S. Araujo, P. D. Thompson, G. F. Fletcher, A. B. de Luna, J. L. Fleg, A. Pelliccia, G. J. Balady, F. Furlanello, S. P. Van Camp, et al. Recommendations for Preparticipation Screening and the Assessment of Cardiovascular Disease in Masters Athletes : An Advisory for Healthcare Professionals From the Working Groups of the World Heart Federation, the International Federation of Sports Medicine, and the American Heart Association Committee on Exercise, Cardiac Rehabilitation, and Prevention Circulation, January 16, 2001; 103(2): 327 - 334. [Full Text] [PDF]

				S. C. Smith Jr, E. Amsterdam, G. J. Balady, R. O. Bonow, G. F. Fletcher, V. Froelicher, G. Heath, M. C. Limacher, J. Maddahi, D. Pryor, et al. Prevention Conference V : Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Tests for Silent and Inducible Ischemia : Writing Group II Circulation, January 4, 2000; 101 (1): e12 - e16. [Full Text] [PDF]

				T. M. Rywik, R. C. Zink, N. S. Gittings, A. A. Khan, J. G. Wright, F. C. O'Connor, and J. L. Fleg Independent Prognostic Significance of Ischemic ST-Segment Response Limited to Recovery From Treadmill Exercise in Asymptomatic Subjects Circulation, June 2, 1998; 97(21): 2117 - 2122. [Abstract] [Full Text] [PDF]

				A. Fowler-Brown, M. Pignone, M. Pletcher, J. A. Tice, S. F. Sutton, and K. N. Lohr Exercise Tolerance Testing To Screen for Coronary Heart Disease: A Systematic Review for the Technical Support for the U.S. Preventive Services Task Force Ann Intern Med, April 6, 2004; 140(7): W-9 - W-24. [Abstract] [Full Text] [PDF]