Circulation, Vol 62, 712-717, Copyright © 1980 by American Heart Association
WL Proudfit, VG Bruschke and FM Sones Jr
The clinical course was followed for 10 years in 521 patients whose
coronary arteriograms did not show any severe obstruction. Coronary disease
had been suspected in all patients before arteriography. Two of 357
patients thought to have normal arteriograms died from coronary disease and
two of 101 patients died who had less than 30% estimated narrowing of at
least one coronary artery. Ten deaths ascribed to coronary disease occurred
in 63 patinets who had 30-50% narrowing of at least one major coronary
artery. The difference in death rates between the normal or mildly diseased
groups and the group that had moderate narrowing was significant (p <
0.01). Coronary events (death from coronary disease, subsequent myocardial
infarction, or arteriographic evidence of progression of coronary
obstruction) occurred in 2.1% of those who had normal arteriograms, 13.8%
of the group with mild lesions, and 33% of those with moderate degree of
coronary arterial narrowing.
ARTICLES
Clinical course of patients with normal or slightly or moderately abnormal coronary arteriograms: 10-year follow-up of 521 patients
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