Circulation, Vol 63, 761-767, Copyright © 1981 by American Heart Association
AF Parisi, PF Moynihan, ED Folland and CL Feldman
The quantitative approaches to the assessment of regional left ventricular
(LV) function described in the preceding paper were applied in a
well-defined population of patients with coronary artery disease. Two
groups were chosen by electrocardiographic and angiographic criteria: group
1 had infarction and regional wall motion abnormalities and group 2 had no
infarction and normal wall motion. Sensitivity to detect wall motion
defects, specificity to correctly categorize normal segments, and overall
predictive accuracy were evaluated for each two- dimensional
echocardiographic approach. In addition, the ability of each method to
localize regional contraction defects properly was evaluated. Area methods
yielded better predictive accuracy than linear methods (87-95% vs 76-84%).
No significant differences in accuracy were noted between quadrant and
octant approaches. The fixed external-axis system was superior to a
floating one for localizing contraction defects. We conclude that an
area-based method, using a fixed-axis system and either octant or quadrant
image subdivision, provides the best combination of predictive accuracy in
categorizing LV segments as normal or abnormal and the greatest ability to
localize LV regional abnormalities.
ARTICLES
Quantitative detection of regional left ventricular contraction abnormalities by two-dimensional echocardiography. II. Accuracy in coronary artery disease
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