Circulation, Vol 64, 945-951, Copyright © 1981 by American Heart Association
GM Jeppson, PD Clayton, TJ Blair, HV Liddle, RL Jensen and SC Klausner
We evaluated changes in ventricular wall motion after surgery by comparing
smoothed, filtered measurements of regional percent shortening (RPS) from
right anterior oblique ventriculograms in 37 patients before and after
surgery. After surgery there was a significant (p less than 0.05) decrease
in the number of regions with hypokinetic wall motion. The distribution of
RPS values was also different (p less than 0.005). However, the mean value
of RPS for the surgery group as a whole was not significantly altered.
These data were contrasted with RPS data from 11 control patients, who were
each studied twice but did not have surgical intervention. Similar analysis
of the control group did not show any significant change between studies in
the number of hypokinetic regions, and the distributions of RPS for the
first and second angiograms were not different. We found a 10.3% absolute
mean change in repeated measurements of RPS in the control group. We
conclude that significant changes occurred after surgery that were not
evident in the control group, and the amount of variability in repeated
measurements of RPS suggests that analysis should be applied to group
rather than individual data.
ARTICLES
Changes in left ventricular wall motion after coronary artery bypass surgery: signal or noise?
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