Circulation, Vol 65, 551-560, Copyright © 1982 by American Heart Association
E Botvinick, R Dunn, M Frais, W O'Connell, D Shosa, R Herfkens and M Scheinman
To determine the relationship of phase changes and abnormalities of
ventricular contraction and conduction, we performed phase image analysis
of blood pool scintigrams in 29 patients. Eleven patients had no evidence
of blood pool contraction or ECG conduction abnormalities, four had
contraction abnormalities, seven had abnormal conduction and seven had
abnormalities of both variables. The phase delay generally related to the
degree of contraction abnormality. The mean phase delay in hypokinetic
segments differed from that in normokinetic segments in the same patient (p
less than 0.025), the phase delay of akinetic and dyskinetic segments
differed from that in normokinetic segments (p less than 0.001) and the
phase delay in dyskinetic segments differed from that in akinetic segments
(p less than 0.005), but there was a significant overlap in the phase delay
in normal and hypokinetic segments. Also, in patients with conduction
abnormalities, the minimal associated regional phase delay presented a
phase dispersion and a pattern of contraction consistent with the pattern
of conduction and different from normal. A single study performed both at
rest and with stress demonstrated the effect of heart rate on phase
assessment and confirmed the independent effects of contraction and
conduction on phase delay. Acquisition and analytic methods should add
significantly to the resolution of the phase method.
ARTICLES
The phase image: its relationship to patterns of contraction and conduction
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