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Circulation, Vol 65, 950-952, Copyright © 1982 by American Heart Association

ARTICLES

Release of atherosclerotic debris after transluminal angioplasty

PC Block, D Elmer and JT Fallon

To determine if there is release of endothelial cells or plaque contents after percutaneous transluminal angioplasty, effluent from atherosclerotic segments of the aorta and iliac arteries of rabbits were collected before and after angioplasty. No endothelial cells or cholesterol plates were identified in the preangioplasty effluents. Only a few single endothelial cells and cholesterol crystals were found in effluents after angioplasty. We conclude that embolization of endothelial fragments and cholesterol plates occurs during angioplasty, but only to a minor degree, and is probably not clinically important.

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