Circulation, Vol 65, 1099-1105, Copyright © 1982 by American Heart Association
A Betriu, A Castaner, GA Sanz, JC Pare, E Roig, S Coll, J Magrina and F Navarro- Lopez
Coronary anatomy as it relates to left ventricular function was assessed
prospectively in patients who survived acute myocardial infarction. The
study population included 259 consecutive male patients age 60 years or
younger who underwent catheterization 30 days after the acute event.
Coronary artery obstructive lesions (greater than 50% reduction in luminal
diameter) were found in 241 patients (93%), 118 (45%) of whom had total and
76 (29%) subtotal (greater than 90%) stenosis) occlusion of at least one
coronary artery. Normal coronary vessels were seen in eight patients (3%)
and nonobstructive lesions in 10 (4%). One-, two- and three-vessel disease
were present in 89, 86 and 66 patients, respectively. Patients with normal
coronary arteries or nonobstructive lesions had higher ejection fractions
than those with obstructive lesions in one, two or three vessels (p less
than 0.05). Ejection fraction was lower (p less than .001) and the
percentage of akinetic segments higher (p less than 0.001) in patients with
total or subtotal lesions and no collaterals. Adequate collaterals, seen in
29 patients (11%), significantly improved regional wall motion (p less than
0.05) and decreased the percentage of akinetic segments (p less than
0.001). Thus, in a substantial number of patients (32% in our series), the
infarcted area is spontaneously reperfused by collaterals or through the
involved artery. Both mechanisms ameliorate wall motion in corresponding
areas.
ARTICLES
Angiographic findings 1 month after myocardial infarction: a prospective study of 259 survivors
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