This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nixon, J. V. Articles by Smitherman, T. C. Search for Related Content PubMed PubMed Citation Articles by Nixon, J. V. Articles by Smitherman, T. C.

Circulation, Vol 65, 1497-1503, Copyright © 1982 by American Heart Association

ARTICLES

Identification of transient and persistent segmental wall motion abnormalities in patients with unstable angina by two-dimensional echocardiography

JV Nixon, CN Brown and TC Smitherman

To determine the value of real-time, two-dimensional echocardiography (2-D echo) in unstable angina, regional wall motion on serial short- axis 2-D echo recordings was analyzed and summed segment scores of abnormal motion were compared and classified according to each patient's clinical status 12 weeks after hospital discharge. Nineteen male patients who fulfilled criteria for unstable angina and responded to medical therapy underwent 2-D echo study within 48 hours of admission and discharge. Of 11 patients with abnormal 2-D echo scores on admission, five patients had reduced scores and six patients had similar or increased scores at discharge. Six of eight patients who had scores of zero on admission had scores of zero at discharge. At follow- up, 11 patients had minimal or no angina pectoris (group 1), and eight patients had worsening angina or recurrent unstable angina (group 2). At discharge, 2-D echo studies showed that all group 1 patients had reduced or zero scores, while group 2 patients retained or increased their abnormal scores. This study shows that in patients with unstable angina, both transient and persistent abnormalities can be identified by 2-D echo. Abnormal segmental wall motion was transient or absent in patients with a good outcome, and worsened or remained abnormal in patients with a poor outcome.

This article has been cited by other articles:

				A. N. Mazzadi, X. Andre-Fouet, N. Costes, P. Croisille, D. Revel, and M. F. Janier Mechanisms leading to reversible mechanical dysfunction in severe CAD: alternatives to myocardial stunning Am J Physiol Heart Circ Physiol, December 1, 2006; 291(6): H2570 - H2582. [Abstract] [Full Text] [PDF]

				M. Hickman, J.M.A. Swinburn, and R. Senior Wall thickening assessment with tissue harmonic echocardiography results in improved risk stratification for patients with non-ST-segment elevation acute chest pain Eur J Echocardiogr, March 1, 2004; 5(2): 142 - 148. [Abstract] [Full Text] [PDF]

				E. o. Cosar and C. J. O'Connor Hibernation, Stunning, and Preconditioning: Historical Perspective, Current Concepts, Clinical Applications, and Future Implications Seminars in Cardiothoracic and Vascular Anesthesia, June 1, 2003; 7(2): 115 - 140. [Abstract] [PDF]

				H. Mahrholdt, A. Wagner, R.M. Judd, and U. Sechtem Assessment of myocardial viability by cardiovascular magnetic resonance imaging Eur. Heart J., April 2, 2002; 23(8): 602 - 619. [Full Text] [PDF]

				R. A. Kloner and R. B. Jennings Consequences of Brief Ischemia: Stunning, Preconditioning, and Their Clinical Implications: Part 1 Circulation, December 11, 2001; 104(24): 2981 - 2989. [Abstract] [Full Text] [PDF]

				F. Haas, L. Jennen, U. Heinzmann, N. Augustin, M. Wottke, M. Schwaiger, and R. Lange Ischemically compromised myocardium displays different time-courses of functional recovery: correlation with morphological alterations? Eur. J. Cardiothorac. Surg., August 1, 2001; 20(2): 290 - 298. [Abstract] [Full Text] [PDF]

				F. Haas, N. Augustin, K. Holper, M. Wottke, C. Haehnel, S. Nekolla, H. Meisner, R.u. Lange, and M. Schwaiger Time course and extent of improvement of dysfunctioning myocardium in patients with coronary artery disease and severely depressed left ventricular function after revascularization: correlation with positron emission tomographic findings J. Am. Coll. Cardiol., November 15, 2000; 36(6): 1927 - 1934. [Abstract] [Full Text] [PDF]

				R. A. Kloner, R. Bolli, E. Marban, L. Reinlib, and E. Braunwald Medical and Cellular Implications of Stunning, Hibernation, and Preconditioning : An NHLBI Workshop Circulation, May 19, 1998; 97(18): 1848 - 1867. [Full Text] [PDF]

				K. S. McDonald, P. P.A. Mammen, K. T. Strang, R. L. Moss, and W. P. Miller Isometric and Dynamic Contractile Properties of Porcine Skinned Cardiac Myocytes After Stunning Circ. Res., November 1, 1995; 77(5): 964 - 972. [Abstract] [Full Text]

				K.M.A. Hussain, L. Gould, E.V. Pomerantsev, M. Angirekula, and T. Bharathan Comparative Study of Left Ventricular Function in Patients with Unstable Angina, Non-Q Wave Myocardial Infarction and Stable Angina Pectoris: Assessment with Atrial Pacing and Digital Ventriculography Angiology, October 1, 1995; 46(10): 867 - 876. [Abstract] [PDF]