Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
« Previous Article | Table of Contents | Next Article »
Circulation. 1983;67:610-613

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Magnoni, M. S.
Right arrow Articles by Trabucchi, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Magnoni, M. S.
Right arrow Articles by Trabucchi, M.
Right arrowPubmed/NCBI databases
Medline Plus Health Information
*High Blood Pressure

Circulation, Vol 67, 610-613, Copyright © 1983 by American Heart Association

ARTICLES

Hypertension reduces the number of beta-adrenergic receptors in rat brain microvessels

MS Magnoni, H Kobayashi, A Cazzaniga, F Izumi, PF Spano and M Trabucchi

Beta-adrenergic receptor function was measured in cerebral microvessels of spontaneously and DOCA-salt hypertensive rats using 125I- iodohydroxybenzylpindolol (IHYP). Both in genetic and in experimental hypertension, a significant decrease in the number of beta-receptor sites was observed, without receptor affinity changes. These results suggest that alterations of central adrenergic regulation of small vessels may participate in the pathogenetic mechanisms leading to the development of the central hypertensive disease.




Circulation Home | Subscriptions | Archives | Feedback | Authors | Help | AHA Journals Home | Search
Copyright © 1983 American Heart Association, Inc. All rights reserved. Unauthorized use prohibited.