This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Curtiss, E. I. Articles by Shapiro, L. S. Search for Related Content PubMed PubMed Citation Articles by Curtiss, E. I. Articles by Shapiro, L. S.

Circulation, Vol 67, 699-701, Copyright © 1983 by American Heart Association

ARTICLES

Pulmonic regurgitation due to valvular tophi

EI Curtiss, TR Miller and LS Shapiro

Documented cardiac tophi are rare and have not previously been reported to cause clinically manifest valvular disease. A 31-year-old male with complex cyanotic congenital heart disease (Taussig-Bing anomaly) and secondary tophaceous gouty arthritis is described. Terminally, he presented with clinical evidence of a brain abscess and a new semilunar regurgitant murmur. Two-dimensional echocardiography suggested vegetative lesions as the cause of the murmur. The patient was treated for infective endocarditis. At autopsy, the cause of the semilunar regurgitant murmur was shown to be sterile tophi located along the line of pulmonary valvular coaptation. Tophaceous deposits were also present in the mitral valve.

This article has been cited by other articles:

				L. E. Spieker, F. T. Ruschitzka, T. F. Luscher, and G. Noll The management of hyperuricemia and gout in patients with heart failure Eur J Heart Fail, August 1, 2002; 4(4): 403 - 410. [Full Text] [PDF]

				R. H. Shmerling, S. H. Stern, E. M. Gravallese, and F. G. Kantrowitz Tophaceous Deposition in the Finger Pads Without Gouty Arthritis Arch Intern Med, August 1, 1988; 148(8): 1830 - 1832. [Abstract] [PDF]