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(Circulation. 1953;7:380.)
© 1953 American Heart Association, Inc.

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Mercurial Diuretics: The Replacement of Parenteral Administration by a New Oral Preparation in Ambulatory Patients with Chronic Congestive Heart Failure

SIM P. DIMITROFF M.D.¹; M. C. THORNER M.D.¹; GEORGE C. GRIFFITH M.D.¹

¹ From the Department of Medicine (Cardiology), School of Medicine, University of Southern California and the Los Angeles County Hospital, Los Angeles, Calif.

Improvement in the usage of an effective therapeutic agent is highly desirable especially when the method of administration is simplified, the total dosage reduced, the toxicity of the drug diminished and the cost of medical care lessened. The replacement of parenteral injections of the mercurial diuretics by an oral preparation in ambulatory patients in chronic congestive heart failure represents a step forward in the management of this type of patient.