Circulation, Vol 70, 547-551, Copyright © 1984 by American Heart Association
PL McHenry, J O'Donnell, SN Morris and JJ Jordan
A group of 916 apparently healthy men between the ages of 27 and 55 years
(mean 37) were followed up with serial medical and exercise test
evaluations for a period of 8 to 15 years (mean 12.7) to determine (1) the
prevalence and specific types of new coronary events observed in subjects
with and without abnormal ST segment responses to exercise and (2) the
predictive value of a serial conversion to an abnormal ST segment response
to exercise for new coronary events. During the initial evaluation there
were 23 subjects (2.5%) with an abnormal ST segment response to exercise.
During follow-up there were nine (39%) coronary events in this group: eight
cases of angina and one of sudden death. With serial testing, an additional
38 subjects (5.1%) experienced conversion to an abnormal ST segment
response to exercise. During follow-up there were 12 (32%) coronary events
in this group: 10 cases of angina, one of myocardial infarction, and one
other. There were 833 subjects with normal ST segment responses to exercise
with all tests. In this group there were 44 (5.3%) coronary events: 25
cases of myocardial infarction, seven of sudden death, and 12 of angina. We
conclude that in apparently healthy middle-aged men an abnormal ST segment
response to exercise is predictive of angina pectoris but not of myocardial
infarction or sudden cardiac death as an initial coronary event.
ARTICLES
The abnormal exercise electrocardiogram in apparently healthy men: a predictor of angina pectoris as an initial coronary event during long- term follow-up
This article has been cited by other articles:
 |
|
 |
|
  G. A. Ewy The Search for the "Holy Grail" of Clinically Significant Coronary Atherosclerosis Arch Intern Med, June 28, 2004; 164(12): 1266 - 1268. [Full Text] [PDF]
|
|
|
|
 |
|
 G. Erikssen, J. Bodegard, J. V. Bjornholt, K. Liestol, D. S. Thelle, and J. Erikssen Exercise testing of healthy men in a new perspective: from diagnosis to prognosis Eur. Heart J., June 1, 2004; 25(11): 978 - 986. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Fowler-Brown, M. Pignone, M. Pletcher, J. A. Tice, S. F. Sutton, and K. N. Lohr Exercise Tolerance Testing To Screen for Coronary Heart Disease: A Systematic Review for the Technical Support for the U.S. Preventive Services Task Force Ann Intern Med, April 6, 2004; 140(7): W-9 - W-24. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. F. Cohn, K. M. Fox, and C. Daly Silent Myocardial Ischemia Circulation, September 9, 2003; 108(10): 1263 - 1277. [Full Text] [PDF]
|
|
|
|
 |
|
 A A Awad-Elkarim, J P Bagger, C J Albers, J S Skinner, P C Adams, and R J C Hall A prospective study of long term prognosis in young myocardial infarction survivors: the prognostic value of angiography and exercise testing Heart, August 1, 2003; 89(8): 843 - 847. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. M. Rywik, F. C. O'Connor, N. S. Gittings, J. G. Wright, A. A. Khan, and J. L. Fleg Role of Nondiagnostic Exercise-Induced ST-Segment Abnormalities in Predicting Future Coronary Events in Asymptomatic Volunteers Circulation, November 26, 2002; 106(22): 2787 - 2792. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. C. Deedwania Silent ischemia predicts poor outcome in high-risk healthy men J. Am. Coll. Cardiol., July 1, 2001; 38(1): 80 - 83. [Full Text] [PDF]
|
|
|
|
 |
|
 M. E. Tavel Stress Testing in Cardiac Evaluation : Current Concepts With Emphasis on the ECG Chest, March 1, 2001; 119(3): 907 - 925. [Full Text] [PDF]
|
|
|
|
|
|
Y. Arad, L. A. Spadaro, K. Goodman, D. Newstein, and A. D. Guerci Prediction of coronary events with electron beam computed tomography J. Am. Coll. Cardiol., October 1, 2000; 36(4): 1253 - 1260. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 X. Jouven, M. Zureik, M. Desnos, D. Courbon, and P. Ducimetiere Long-Term Outcome in Asymptomatic Men with Exercise-Induced Premature Ventricular Depolarizations N. Engl. J. Med., September 21, 2000; 343(12): 826 - 833. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. C. Smith Jr, E. Amsterdam, G. J. Balady, R. O. Bonow, G. F. Fletcher, V. Froelicher, G. Heath, M. C. Limacher, J. Maddahi, D. Pryor, et al. Prevention Conference V : Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Tests for Silent and Inducible Ischemia : Writing Group II Circulation, January 4, 2000; 101 (1): e12 - e16. [Full Text] [PDF]
|
|
|
|
|
|
U. Sechtem Electron beam computed tomography: on its way into mainstrem cardiology? Eur. Heart J., January 2, 2000; 21(2): 87 - 91. [PDF]
|
|
|
|
 |
|
 Y. Nagai, E J. Metter, and J. L Fleg Increased carotid artery intimal-medial thickness: risk factor for exercise-induced myocardial ischemia in asymptomatic older individuals Vascular Medicine, August 1, 1999; 4(3): 181 - 186. [Abstract] [PDF]
|
|
|
|
|
|
T. M. Rywik, R. C. Zink, N. S. Gittings, A. A. Khan, J. G. Wright, F. C. O'Connor, and J. L. Fleg Independent Prognostic Significance of Ischemic ST-Segment Response Limited to Recovery From Treadmill Exercise in Asymptomatic Subjects Circulation, June 2, 1998; 97(21): 2117 - 2122. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. D. Thompson The Cardiovascular Complications of Vigorous Physical Activity Arch Intern Med, November 11, 1996; 156(20): 2297 - 2302. [Abstract] [PDF]
|
|
|
|
|
|
B. Pitt Evaluation of the Postinfarct Patient Circulation, March 15, 1995; 91(6): 1855 - 1860. [Full Text]
|
|
|
|
|
|
G. F. Fletcher, G. Balady, V. F. Froelicher, L. H. Hartley, W. L. Haskell, and M. L. Pollock Exercise Standards : A Statement for Healthcare Professionals From the American Heart Association Circulation, January 15, 1995; 91(2): 580 - 615. [Full Text]
|
|
|
|
|
|
M. M. Bodenheimer Risk Stratification in Coronary Disease: A Contrary Viewpoint Ann Intern Med, June 1, 1992; 116(11): 927 - 936. [Abstract] [PDF]
|
|
|
|
 |
|
 N. Hamouratidis, N. Katsaliakis, F. Manoudis, K. Lazaridis, T. Tselegaridis, V. Stravelas, E. Simeonidou, and S. Roussis Early Exercise Test in Acute Myocardial Infarction Treated with Intravenous Streptokinase Angiology, September 1, 1991; 42(9): 696 - 702. [Abstract] [PDF]
|
|
|
|
|
|
D. S. Siscovick, L. G. Ekelund, J. L. Johnson, Y. Truong, and A. Adler Sensitivity of Exercise Electrocardiography for Acute Cardiac Events During Moderate and Strenuous Physical Activity: The Lipid Research Clinics Coronary Primary Prevention Trial Arch Intern Med, February 1, 1991; 151(2): 325 - 330. [Abstract] [PDF]
|
|
|
|
|
|
R. DETRANO and V. FROELICHER A Logical Approach to Screening for Coronary Artery Disease Ann Intern Med, June 1, 1987; 106(6): 846 - 852. [Abstract] [PDF]
|
|
|
|
|
|
A. Fowler-Brown, M. Pignone, M. Pletcher, J. A. Tice, S. F. Sutton, and K. N. Lohr Exercise Tolerance Testing To Screen for Coronary Heart Disease: A Systematic Review for the Technical Support for the U.S. Preventive Services Task Force Ann Intern Med, April 6, 2004; 140(7): W-9 - W-24. [Abstract] [Full Text] [PDF]
|
|