Circulation, Vol 72, 440-447, Copyright © 1985 by American Heart Association
D Burkhoff, E van der Velde, D Kass, J Baan, WL Maughan and K Sagawa
We evaluated the accuracy of the recently reported technique of estimating
intraventricular volume by measurement of intracavitary electrical
conductance in six isolated, ejecting, canine left ventricles. Left
ventricular volumes were measured directly by a previously validated
servosystem that employed an electroconductive balloon placed in the left
ventricular cavity. The volume measured continuously by the balloon method
(Vbal) was compared with that estimated by the conductance method (Vcath).
For this test, the hearts were made to eject and fill physiologically by
the use of a previously described computer-simulated arterial loading
system. Complex ejection and filling patterns were created by stimulating
the atrium mechanically, which resulted in irregular arrhythmatic
contractions spanning a wide range of volumes. We found that there was a
highly linear relationship (r2 = .982 +/- .014) between Vbal and Vcath:
Vcath = 0.82 (+/- .05) Vbal + 26.7 (+/- 11.8) ml. Despite the wide
variation in the offset term of this relationship among the different
hearts, the offset within a given heart was predicted within 3.5 ml by a
previously detailed "dilution" method that is applicable to the heart in
situ within a closed thorax. Thus, since the offset term is obtainable in
situ, the conductance method provides a signal that is proportional to the
actual volume. To determine whether right ventricular volume influenced the
accuracy of left ventricular measurement, we compared the relationship
between Vcath and Vbal obtained with right ventricular volumes of 0 and 30
ml. Increasing the right ventricular volume shifted the relationship upward
by less than 3 ml in the working range.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Accuracy of volume measurement by conductance catheter in isolated, ejecting canine hearts
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