Circulation, Vol 72, 1008-1014, Copyright © 1985 by American Heart Association
E Trowitzsch, SD Colan and SP Sanders
Echocardiographic assessment of right ventricular size, global function,
and regional wall motion was performed in 29 normal infants and 19 infants
with transposition of the great arteries 1 to 41 months after they
underwent the Senning procedure. Sixteen of the patients with transposition
of the great arteries were in clinically good condition and three had
congestive heart failure. The right ventricular endocardial surface was
digitized frame by frame for a complete cardiac cycle in both subxiphoid
long-axis (coronal plane) and short-axis (parasagittal plane) views, and
the cross-sectional area and the area change fraction (AF) were calculated.
In each plane the right ventricular wall was subdivided into four anatomic
regions (infundibular, free wall, diaphragmatic, and septal). With the use
of a floating point center of mass model the direction and average extent
of motion of the endocardium was determined for each region. In normal
infants the infundibular and free wall portions of the right ventricle
exhibited the greatest inward motion and the septal segments the least
inward motion. Although the maximal area in both long-axis (r = .85) and
short-axis (r = .85) views was highly correlated with body surface area
(BSA), neither global nor regional function was significantly correlated
with age or BSA. In clinically well patients after Senning procedure
regional right ventricular function followed an entirely different pattern
than that seen in normal infants. The endocardium of the septal segments
showed the greatest inward motion in systole. In contrast to those in
normal infants, maximal and minimal cross- sectional areas did not
correlate significantly with BSA.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Global and regional right ventricular function in normal infants and infants with transposition of the great arteries after Senning operation
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