Circulation, Vol 73, 579-585, Copyright © 1986 by American Heart Association
S Nakao, PC Come, MJ Miller, S Momomura, P Sahagian, BJ Ransil and W Grossman
Hemodynamic measurements in human subjects and in experimental animals are
generally made in the supine position; not much attention is paid to
potential beneficial or harmful effects of right or left lateral positions
on cardiac output or other hemodynamic variables. To evaluate the potential
influence of such positional changes on cardiac performance, we measured
cardiac output and left and right ventricular pressures (with
micromanometer catheters) in anesthetized experimental animals (eight dogs
and nine pigs) in the supine, right lateral, and left lateral positions.
Cardiac output increased from supine to left lateral (mean +/- SD, 2.6 +/-
0.9 to 3.1 +/- 1.0 liters/min; p less than .001) and from supine to right
lateral positions (2.6 +/- 0.9 to 3.1 +/- 1.1 liters/min; p less than
.001). There was an associated decrease in arteriovenous oxygen saturation
difference from supine to left lateral position (31 +/- 8% to 24 +/- 4%; p
less than .001) and from supine to right lateral position (32 +/- 9% to 25
+/- 6%; p less than .001). Left ventricular systolic and end-diastolic
pressures increased from supine to left lateral (128 +/- 17/9 +/- 2 to 147
+/- 19/16 +/- 4 mm Hg; both p less than .001) and from supine to right
lateral positions (128 +/- 19/9 +/- 2 to 141 +/- 16/16 +/- 7 mm Hg; p less
than .01 and p less than .001, respectively).(ABSTRACT TRUNCATED AT 250
WORDS)
ARTICLES
Effects of supine and lateral positions on cardiac output and intracardiac pressures: an experimental study
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