Circulation, Vol 73, 892-899, Copyright © 1986 by American Heart Association
K Isaaz, JL Cloez, F Marcon, AM Worms and C Pernot
The embryogenesis of tetralogy of Fallot is still much debated. In
particular, the dextroposition of the aorta is not considered by all
pathologists as a genuine abnormality in this congenital heart disease but
rather as a false impression due to an exaggeration of the normal
overriding caused by dilatation of the aorta secondary to abnormal
hemodynamics. We used two-dimensional echocardiography to examine the
spatial position of the aortic root in 22 patients with tetralogy of Fallot
(aged 5 days to 24 years, mean 6.4 years) and in 23 normal subjects (aged 1
month to 27 years, mean 7.6 years). Using the parasternal short-axis view,
we determined the percent rightward displacement of the aortic root in
relation to the plane of the atrial septum, and the relationship between
the aortic cusps and the atrial septum. We measured the value of the angle
luminal diameter, which was defined as the angle between the plane of the
atrial septum and the plane of the left coronary-noncoronary commissure and
leaflet appositional plane. In the control group, the aortic root was
displaced to the right by only 23.6 +/- 7.6%; the atrial septum crossed the
posterior aspect of the aortic root at the middle (n = 19) or at the right
half of the posterior cusp (n = 4), and the angle luminal diameter had a
value of 43.3 +/- 8.8 degrees. In the 22 patients with tetralogy, the
percent rightward shift of the aortic root was augmented to 55.5 +/- 9% (p
less than .001) and the atrial septum was related to the posterior
commissure in 14 patients.(ABSTRACT TRUNCATED AT 250 WORDS)
ARTICLES
Is the aorta truly dextroposed in tetralogy of Fallot? A two- dimensional echocardiographic answer
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