This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mehdirad, A. A. Articles by Chaitman, B. R. Search for Related Content PubMed PubMed Citation Articles by Mehdirad, A. A. Articles by Chaitman, B. R.

Circulation, Vol 75, 413-419, Copyright © 1987 by American Heart Association

ARTICLES

Evaluation of left ventricular function during upright exercise: correlation of exercise Doppler with postexercise two-dimensional echocardiographic results

AA Mehdirad, GA Williams, AJ Labovitz, RJ Bryg and BR Chaitman

The relationship of regional and global left ventricular function to aortic flow dynamics during exercise was determined in 14 normal subjects and 14 patients with coronary artery disease. Doppler and two- dimensional echocardiographic studies were performed before, during, and immediately after an exercise test by the Bruce protocol. Two- dimensional echocardiography was used to determine the ejection fraction and new wall motion abnormalities. The peak ejection velocity, stroke index, and cardiac index were calculated from the pulsed Doppler tracing. In normal subjects the ejection fraction increased significantly (p less than .001) from rest (0.51 +/- 0.07) to peak exercise (0.61 +/- 0.07), while the response in coronary patients was blunted (0.49 +/- 0.11 vs 0.48 +/- 0.16). Similarly, the change in peak ejection velocity throughout exercise in normal subjects (from 0.71 +/- 0.12 to 1.50 +/- 0.35 m/sec) was significantly (p less than .01) greater than that in patients with coronary artery disease (from 0.61 +/- 0.13 to 0.90 +/- 0.29 m/sec). There was a good correlation between the percent change in peak ejection velocity and the percent change in ejection fraction from rest to peak exercise in the entire study group (rs = .64) and in the patients with coronary artery disease (rs = .84). These preliminary data suggest that exercise-induced changes in Doppler echocardiographic variables may offer a potential adjunct in the evaluation of patients with ischemic heart disease.

This article has been cited by other articles:

				L. H. Michael, C. M. Ballantyne, J. P. Zachariah, K. E. Gould, J. S. Pocius, G. E. Taffet, C. J. Hartley, T. T. Pham, S. L. Daniel, E. Funk, et al. Myocardial infarction and remodeling in mice: effect of reperfusion Am J Physiol Heart Circ Physiol, August 1, 1999; 277(2): H660 - H668. [Abstract] [Full Text] [PDF]

				A. C. Fiore, H. B. Barner, M. T. Swartz, L. R. McBride, A. J. Labovitz, K. J. Vaca, J. St. Vrain, G. L. Grunkemeier, and G. C. Kaiser Mitral valve replacement: randomized trial of St. Jude and Medtronic Hall prostheses Ann. Thorac. Surg., September 1, 1998; 66(3): 707 - 713. [Abstract] [Full Text] [PDF]