Circulation, Vol 79, 706-711, Copyright © 1989 by American Heart Association
EP Shapiro, WJ Rogers, R Beyar, RL Soulen, EA Zerhouni, JA Lima and JL Weiss
Measurement of left ventricular (LV) mass by magnetic resonance imaging
(MRI) is accurate in normal hearts. Because determination of mass by MRI
does not require assumptions about ventricular shape, this method may be
well suited for evaluating hearts distorted by infarction. To test this
hypothesis, gated MRI was performed in 15 dogs before and after acute
myocardial infarction. The LV mass of each dog was calculated from five
short-axis images acquired at end systole, when shape distortion is
greatest, at end diastole, and also from slices at varying phases of the
cycle with a multiphase mode that required only one acquisition.
Correlation was excellent between actual mass and end- systolic mass before
infarction (p less than 0.001, r = 0.98, and SEE = 5.1 g) and after
infarction (p less than 0.001, r = 0.97, and SEE = 6.6 g). Likewise, values
correlated closely at end diastole before (p less than 0.001, r = 0.96, and
SEE = 6.7 g) and after infarction (p less than 0.001, r = 0.94, and SEE =
8.7 g). Surprisingly, measurements of mass by a multiphase mode were also
very accurate before (p less than 0.001, r = 0.98, and SEE = 5.1 g) and
after (p less than 0.001, r = 0.95, and SEE = 6.49 g) infarction.
Therefore, at the same phase and at multiphases of the cardiac cycle, MRI
permits accurate determination of LV mass in distorted hearts.
ARTICLES
Determination of left ventricular mass by magnetic resonance imaging in hearts deformed by acute infarction
Francis Scott Key Medical Center, Baltimore, Maryland.
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