This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ropella, K. M. Articles by Swiryn, S. Search for Related Content PubMed PubMed Citation Articles by Ropella, K. M. Articles by Swiryn, S.

Circulation, Vol 80, 112-119, Copyright © 1989 by American Heart Association

ARTICLES

The coherence spectrum. A quantitative discriminator of fibrillatory and nonfibrillatory cardiac rhythms

KM Ropella, AV Sahakian, JM Baerman and S Swiryn
Department of Biomedical Engineering, Northwestern University, Evanston, Illinois.

Previous work has suggested that a comparison of electrograms from two or more sites may best differentiate fibrillatory from nonfibrillatory rhythms. The coherence spectrum is a measure by which two signals may be compared quantitatively in the frequency domain. In the present study, the coherence spectrum was used to quantify the relation between spectral components of electrograms from two sites in either the atrium or ventricle during both fibrillatory and nonfibrillatory rhythms. Bipolar recordings of 35 rhythms from 20 patients were analyzed for coherence in the 1-59 Hz band. The 17 nonfibrillatory rhythms were sinus rhythm (six), paroxysmal supraventricular tachycardia (two), atrial flutter (four), and monomorphic ventricular tachycardia (five). The 18 fibrillatory rhythms were atrial fibrillation (12) and ventricular fibrillation (six). Nonfibrillatory rhythms exhibited moderate-to-high levels of coherence throughout the 1-59 Hz band, with peaks concentrated at the rhythm's fundamental frequency and its harmonics. Fibrillatory rhythms exhibited little coherence throughout the 1-59 Hz band, and harmonics were not evident. The mean magnitude- squared coherence (scale of 0 to 1) for the 1-59 Hz band ranged from 0.22 to 0.86 (mean +/- SD, 0.52 +/- 0.19) for nonfibrillatory rhythms and from 0.042 to 0.12 (0.067 +/- 0.021) for fibrillatory rhythms. Separation of fibrillatory and nonfibrillatory rhythms was possible whether signals were recorded by floating or fixed-electrode configurations. These findings indicate that comparison of two electrograms with magnitude-squared coherence measurements differentiates fibrillatory from nonfibrillatory rhythms. A recognition algorithm based on coherence spectra may provide a major variations in lead configuration.(ABSTRACT TRUNCATED AT 250 WORDS)

This article has been cited by other articles:

				Y.-J. Lin, C.-T. Tai, T. Kao, H.-W. Tso, J.-L. Huang, S. Higa, Y. Yuniadi, B.-H. Huang, T.-Y. Liu, P.-C. Lee, et al. Electrophysiological Characteristics and Catheter Ablation in Patients With Paroxysmal Right Atrial Fibrillation Circulation, September 20, 2005; 112(12): 1692 - 1700. [Abstract] [Full Text] [PDF]

				J. Huang, J. M. Rogers, C. R. Killingsworth, K. P. Singh, W. M. Smith, and R. E. Ideker Evolution of activation patterns during long-duration ventricular fibrillation in dogs Am J Physiol Heart Circ Physiol, March 1, 2004; 286(3): H1193 - H1200. [Abstract] [Full Text] [PDF]

				S. Higa, C.-T. Tai, Y.-J. Lin, T.-Y. Liu, P.-C. Lee, J.-L. Huang, M.-H. Hsieh, Y. Yuniadi, B.-H. Huang, S.-H. Lee, et al. Focal Atrial Tachycardia: New Insight From Noncontact Mapping and Catheter Ablation Circulation, January 6, 2004; 109(1): 84 - 91. [Abstract] [Full Text] [PDF]

				A. Kadish, D. Johnson, W. Choe, J. Goldberger, and G. Horvath Characterization of fibrillatory rhythms by ensemble vector directional analysis Am J Physiol Heart Circ Physiol, October 1, 2003; 285(4): H1705 - H1719. [Abstract] [Full Text] [PDF]

				F. H Samie and J. Jalife Mechanisms underlying ventricular tachycardia and its transition to ventricular fibrillation in the structurally normal heart Cardiovasc Res, May 1, 2001; 50(2): 242 - 250. [Abstract] [Full Text] [PDF]

				H. J. Sih, D. P. Zipes, E. J. Berbari, D. E. Adams, and J. E. Olgin Differences in organization between acute and chronic atrial fibrillation in dogs J. Am. Coll. Cardiol., September 1, 2000; 36(3): 924 - 931. [Abstract] [Full Text] [PDF]

				A. Kadish, J. Hauck, B. Pederson, G. Beatty, and C. Gornick Mapping of Atrial Activation With a Noncontact, Multielectrode Catheter in Dogs Circulation, April 13, 1999; 99(14): 1906 - 1913. [Abstract] [Full Text] [PDF]

				F. Gaita, R. Riccardi, L. Calo, M. Scaglione, L. Garberoglio, R. Antolini, M. Kirchner, F. Lamberti, and E. Richiardi Atrial Mapping and Radiofrequency Catheter Ablation in Patients With Idiopathic Atrial Fibrillation : Electrophysiological Findings and Ablation Results Circulation, June 2, 1998; 97(21): 2136 - 2145. [Abstract] [Full Text] [PDF]

				G. W. Botteron and J. M. Smith Quantitative Assessment of the Spatial Organization of Atrial Fibrillation in the Intact Human Heart Circulation, February 1, 1996; 93(3): 513 - 518. [Abstract] [Full Text]

				W. Xu, H.-F. Tse, F. H.Y. Chan, P. C. W. Fung, K. L.-F. Lee, and C.-P. Lau New Bayesian Discriminator for Detection of Atrial Tachyarrhythmias Circulation, March 26, 2002; 105(12): 1472 - 1479. [Abstract] [Full Text] [PDF]