Circulation, Vol 80, 1706-1710, Copyright © 1989 by American Heart Association
NN Musewe, LN Benson, JF Smallhorn and RM Freedom
To evaluate the results of ductal occlusion with the Rashkind prosthesis,
78 children (group 1, 19 boys and 59 girls; mean age at occlusion, 4.5 +/-
4.0 years) with isolated patent ductus arteriosus (n = 73) or in
association with other lesions (n = 5) were evaluated by pulsed and color
flow Doppler 9 +/- 7 months (range, 2-26 months) after occlusion. Thirty
children who had undergone patent ductus arteriosus ligation (group 2, 9
boys and 21 girls; mean age at study, 5.7 +/- 4.9 years; mean follow-up
after ligation, 44 +/- 58 months) were evaluated in the same way. The
prevalence of residual ductal shunting and the main pulmonary arterial flow
patterns were recorded. Residual ductal shunting in group 1 was 38% on day
1, decreasing slowly to 31% at 3 months, 27% at 6 months, and 19.7% at 1
year or more due to further spontaneous shunt resolution. The residual
shunting rate in group 2 (6%) was significantly lower than that at 1 year
or more in group 1 (p less than 0.001). Successful reocclusion in 5 of 6 in
a subset of patients in group 1 followed for 1 year or less reduced further
the prevalence of residual shunting. Residual shunting after patent ductus
arteriosus occlusion is more common than after ligation, but continues to
decrease during follow-up.
ARTICLES
Two-dimensional echocardiographic and color flow Doppler evaluation of ductal occlusion with the Rashkind prosthesis
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
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