This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Moulton, K. P. Articles by Lazzara, R. Search for Related Content PubMed PubMed Citation Articles by Moulton, K. P. Articles by Lazzara, R.

Circulation, Vol 81, 1245-1251, Copyright © 1990 by American Heart Association

ARTICLES

Premature ventricular complex morphology. A marker for left ventricular structure and function

KP Moulton, T Medcalf and R Lazzara
Department of Medicine, Oklahoma Medical Center, Oklahoma City 73190.

The shape of a premature ventricular complex (PVC) might reflect the presence or absence of myocardial disease. To test this, 100 patients with a PVC on a 12-lead electrocardiogram at cardiac catheterization or nuclear angiography were classified according to PVC morphology. Group 1 (n = 50) had PVC QRS complexes with either smooth and uninterrupted contour or with narrow (less than 40 msec) notching. Group 2 (n = 50) demonstrated PVC with broad (greater than or equal to 40 msec) notching or shelves. Clinical, electrocardiographic and angiographic variables were assessed to define group differences. All patients had one or more etiological forms of heart disease none of which distinguished either group. Groups 1 and 2 differed with respect to a history of congestive heart failure (12% vs. 66%, p = 0.0004), dilated cardiomyopathy (2% vs. 38%, p = 0.0005), and the presence of mitral regurgitation (13% vs. 58%, p = 0.001), respectively. In group 1, 45 of 50 (90%) patients with a PVC had no notching. Patients in group 2 had greater PVC QRS duration as compared with patients in group 1 (181 +/- 6 vs. 134 +/- 3 msec, p = 0.0001). End-diastolic volume index (EDVI) (78 +/- 3 vs. 139 +/- 11 ml/m2, p = 0.0000) and ejection fraction (EF) (0.59 +/- 0.02 vs. 0.34 +/- 0.03, p = 0.0000) significantly discriminated between group 1 and 2, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)

This article has been cited by other articles:

				M. K. Das, H. Suradi, W. Maskoun, M. A. Michael, C. Shen, J. Peng, G. Dandamudi, and J. Mahenthiran Fragmented Wide QRS on a 12-Lead ECG: A Sign of Myocardial Scar and Poor Prognosis Circ Arrhythm Electrophysiol, October 1, 2008; 1(4): 258 - 268. [Abstract] [Full Text] [PDF]

				M. M. Gallagher, M. Padula, M. Sgueglia, L. Santini, P. Voci, N. G. Mahon, Y. G. Yap, and F. Romeo Electrocardiographic markers of structural heart disease and predictors of death in 2332 unselected patients undergoing outpatient Holter recording Europace, December 1, 2007; 9(12): 1203 - 1208. [Abstract] [Full Text] [PDF]

				R. L. Murkofsky, G. Dangas, J. A. Diamond, D. Mehta, A. Schaffer, and J. A. Ambrose A prolonged QRS duration on surface electrocardiogram is a specific indicator of left ventricular dysfunction J. Am. Coll. Cardiol., August 1, 1998; 32(2): 476 - 482. [Abstract] [Full Text] [PDF]