Circulation, Vol 81, 1568-1574, Copyright © 1990 by American Heart Association
LG Ekelund, CM Suchindran, JM Karon, RP McMahon and HA Tyroler
After exclusion of persons on blood pressure medication or with prevalent
cardiovascular disease, we studied 83 black and 2,548 white men and 113
black and 1,519 white women 20-69 years old from the Lipid Research Clinics
population sample who had performed a standardized treadmill exercise test.
Resting systolic and diastolic blood pressures were similar in black and
white men, but the diastolic pressure was significantly higher in black
than in white women (81.4 vs 77.4 mm Hg). Body weight was higher in black
than in white women, and reported physical activity was higher in black
than in white men. The proportion of smokers was somewhat higher in blacks
than in whites. During the treadmill exercise test with a modified Bruce
protocol, mean systolic blood pressure at stage 2 was 174 mm Hg in black
men and 166 mm Hg in white men (p less than 0.02), but stage 2 blood
pressures did not differ between black and white women (153 and 152 mm Hg,
respectively). Even after adjustments were made for levels of baseline
characteristics (age, weight, resting systolic blood pressure, smoking, low
density lipoprotein cholesterol, physical activity, and alcohol intake),
black men responded with a 7-mm Hg higher systolic blood pressure during
exercise than white men (p less than 0.01). Another new finding was a
highly significant positive association between stage 2 systolic blood
pressure and low density lipoprotein cholesterol in men. The findings
suggest a higher systemic vascular resistance during exercise in the
selected sample of black men, which is consistent with the higher incidence
of hypertension in black men.
ARTICLES
Black-white differences in exercise blood pressure. The Lipid Research Clinics Program Prevalence Study
Department of Medicine, University of North Carolina, Chapel Hill.
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