This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hayashida, W. Articles by Kawai, C. Search for Related Content PubMed PubMed Citation Articles by Hayashida, W. Articles by Kawai, C. Pubmed/NCBI databases Medline Plus Health Information Cardiomyopathy

Circulation, Vol 82, 2075-2083, Copyright © 1990 by American Heart Association

ARTICLES

Left ventricular regional wall stress in dilated cardiomyopathy

W Hayashida, T Kumada, R Nohara, H Tanio, M Kambayashi, N Ishikawa, Y Nakamura, Y Himura and C Kawai
Department of Internal Medicine, Faculty of Medicine, Kyoto University, Japan.

Left ventriculography with simultaneous pressure micromanometry was performed in 11 normal control subjects and 17 patients with dilated cardiomyopathy (DCM). Left ventricular silhouettes in the right anterior oblique projection were divided into eight areas, and regional wall stress was computed by Janz's method in each area excluding the two most basal areas. Wall stress was higher in DCM patients than in control subjects (p less than 0.01). The percent area changes from end diastole to end systole in each area were lower in DCM patients than in control subjects (mean for six areas, 22 +/- 14% versus 54 +/- 9%, respectively, p less than 0.01), but the coefficient of variation for the percent area changes in the six areas of the left ventricle in DCM patients was greater than that in control subjects (32 +/- 17% versus 15 +/- 4%, respectively, p less than 0.01), indicating regional differences in hypokinesis. There was a significant negative correlation between end-systolic regional wall stress and percent area change (r = -0.60 to -0.86, p less than 0.05) in each area. Thus, excessive regional afterload may play an important role in causing regional hypokinesis in DCM.

This article has been cited by other articles:

				L. Zhong, Y. Su, S.-Y. Yeo, R.-S. Tan, D. N. Ghista, and G. Kassab Left ventricular regional wall curvedness and wall stress in patients with ischemic dilated cardiomyopathy Am J Physiol Heart Circ Physiol, March 1, 2009; 296(3): H573 - H584. [Abstract] [Full Text] [PDF]

				P. Knaapen, M. J. W. Gotte, W. J. Paulus, J. J. M. Zwanenburg, P. A. Dijkmans, R. Boellaard, J. T. Marcus, J. W. R. Twisk, C. A. Visser, A. C. van Rossum, et al. Does Myocardial Fibrosis Hinder Contractile Function and Perfusion in Idiopathic Dilated Cardiomyopathy? PET and MR Imaging Study. Radiology, August 1, 2006; 240(2): 380 - 388. [Abstract] [Full Text] [PDF]

				A. Lembcke, S. Dushe, C. N.H. Enzweiler, C. Kloeters, T. H. Wiese, K.-G. A. Hermann, B. Hamm, and W. F. Konertz Passive external cardiac constraint improves segmental left ventricular wall motion and reduces akinetic area in patients with non-ischemic dilated cardiomyopathy Eur. J. Cardiothorac. Surg., January 1, 2004; 25(1): 84 - 90. [Abstract] [Full Text] [PDF]

				N. Hassan, J.-M. Escanye, Y. Juilliere, P.-Y. Marie, N. David, P. Olivier, A. Ayalew, G. Karcher, J.-F. Stolz, and A. Bertrand 201Tl SPECT Abnormalities, Documented at Rest in Dilated Cardiomyopathy, Are Related to a Lower Than Normal Myocardial Thickness but Not to an Excess in Myocardial Wall Stress J. Nucl. Med., April 1, 2002; 43(4): 451 - 457. [Abstract] [Full Text] [PDF]

				R. M. de Jong, J. H. Cornel, H. J.G.M. Crijns, and D. J. van Veldhuisen Abnormal contractile responses during dobutamine stress echocardiography in patients with idiopathic dilated cardiomyopathy Eur J Heart Fail, August 1, 2001; 3(4): 429 - 436. [Abstract] [Full Text] [PDF]

				A. A. Young, S. Dokos, K. A. Powell, B. Sturm, A. D. McCulloch, R. C. Starling, P. M. McCarthy, and R. D. White Regional heterogeneity of function in nonischemic dilated cardiomyopathy Cardiovasc Res, February 1, 2001; 49(2): 308 - 318. [Abstract] [Full Text] [PDF]

				J. J. Schreuder, P. Steendijk, F. H. van der Veen, O. Alfieri, T. van der Nagel, R. Lorusso, J.-M. van Dantzig, K. B. Prenger, J. Baan, H. J. J. Wellens, et al. Acute and short-term effects of partial left ventriculectomy in dilated cardiomyopathy: Assessment by pressure-volume loops J. Am. Coll. Cardiol., December 1, 2000; 36(7): 2104 - 2114. [Abstract] [Full Text] [PDF]

				E. A. Bocchi, A. Esteves-Filho, G. Bellotti, F. Bacal, L. F. Moreira, N. Stolf, and J. F. Ramires Left ventricular regional wall motion, ejection fraction, and geometry after partial left ventriculectomy. Influence of associated mitral valve repair Eur. J. Cardiothorac. Surg., October 1, 2000; 18(4): 458 - 465. [Abstract] [Full Text] [PDF]

				G. S. Nelson, C. W. Curry, B. T. Wyman, A. Kramer, J. Declerck, M. Talbot, M. R. Douglas, R. D. Berger, E. R. McVeigh, and D. A. Kass Predictors of Systolic Augmentation From Left Ventricular Preexcitation in Patients With Dilated Cardiomyopathy and Intraventricular Conduction Delay Circulation, June 13, 2000; 101(23): 2703 - 2709. [Abstract] [Full Text] [PDF]

				P. Balzer, A. Furber, S. Delepine, F. Rouleau, F. Lethimonnier, O. Morel, A. Tadei, P. Jallet, P. Geslin, and J.-J. le Jeune Regional assessment of wall curvature and wall stress in left ventricle with magnetic resonance imaging Am J Physiol Heart Circ Physiol, September 1, 1999; 277(3): H901 - H910. [Abstract] [Full Text] [PDF]

				J.J. Schreuder, F.H. van der Veen, E.T. van der Velde, F. Delahaye, O. Alfieri, O. Jegaden, R. Lorusso, J.R.C. Jansen, S.A.A.P. Hoeksel, G. Finet, et al. Left Ventricular Pressure-Volume Relationships Before and After Cardiomyoplasty in Patients With Heart Failure Circulation, November 4, 1997; 96(9): 2978 - 2986. [Abstract] [Full Text]

				F. Kohno, T. Kumada, M. Kambayashi, W. Hayashida, N. Ishikawa, and S. Sasayama Change in Aortic End-Systolic Pressure by Alterations in Loading Sequence and Its Relation to Left Ventricular Isovolumic Relaxation Circulation, June 1, 1996; 93(11): 2080 - 2087. [Abstract] [Full Text]