Circulation, Vol 86, 1501-1515, Copyright © 1992 by American Heart Association
JW Kirklin, EH Blackstone, CI Tchervenkov and AR Castaneda
BACKGROUND. As the probability increases that the arterial switch operation
is optimal treatment for transposition, detailed information about outcomes
and the circumstances in which they are suboptimal becomes important.
METHODS AND RESULTS. A multi-institutional prospective study with annual
detailed follow-up included 513 neonates with simple transposition or
transposition and ventricular septal defect entering for diagnosis and
treatment at < 15 days of age and undergoing an arterial switch repair.
The 1-month and 1- and 5-year survivals were 84%, 82%, and 82%,
respectively. The hazard function for death had a rapidly declining single
phase that approached zero by 12 months after surgery. Among the eight
patients who died > or = 3 months after the operation, four had severe
ventricular dysfunction, probably related to imperfect coronary arterial
transfer. Coexisting single ventricular septal defect was not a risk factor
for death. Origin of the left main coronary artery or only the left
anterior descending or the circumflex artery from the right posterior sinus
(sinus 2) was a risk factor that was even stronger when an intramural
course was present; multiplicity of ventricular septal defects was a risk
factor. Longer global myocardial ischemic time and total circulatory arrest
time were risk factors. Certain institutions were shown to be risk factors
for death; the results in some improved with increasing experience, in some
they did not, and in some they worsened. CONCLUSIONS. Good early and
intermediate-term clinical outcomes can be obtained in neonates with simple
transposition and transposition and ventricular septal defect by use of the
arterial switch operation. Certain coronary artery patterns and certain
institutions lessen the goodness of outcome.
ARTICLES
Clinical outcomes after the arterial switch operation for transposition. Patient, support, procedural, and institutional risk factors. Congenital Heart Surgeons Society
Division of Cardiothoracic Surgery, University of Alabama, Birmingham Medical Center 35294.
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|
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|
|
|
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|
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|
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|
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|
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|
|
|
|
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|
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|
|
|
|
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|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
|
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
 M. Gutberlet, T. Boeckel, N. Hosten, M. Vogel, T. Kühne, H. Oellinger, T. Ehrenstein, S. Venz, R. Hetzer, G. Bein, et al. Arterial Switch Procedure for D-Transposition of the Great Arteries: Quantitative Midterm Evaluation of Hemodynamic Changes with Cine MR Imaging and Phase-Shift Velocity Mapping-Initial Experience Radiology, February 1, 2000; 214(2): 467 - 475. [Abstract] [Full Text]
|
|
|
|
|
|
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|
|
|
|
|
|
E. Belli, F. Lacour-Gayet, A. Serraf, A. M. Alkhulaifi, A. Touchot, J. Bruniaux, and C. Planche Surgical management of transposition of great arteries associated with multiple ventricular septal defects Eur. J. Cardiothorac. Surg., July 1, 1999; 16(1): 14 - 20. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. D. Blume, K. Altmann, J. E. Mayer, S. D. Colan, K. Gauvreau, and T. Geva Evolution of risk factors influencing early mortality of the arterial switch operation J. Am. Coll. Cardiol., May 1, 1999; 33(6): 1702 - 1709. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. V. Maeno, S. A. Kamenir, B. Sinclair, M. E. van der Velde, J. F. Smallhorn, and L. K. Hornberger Prenatal Features of Ductus Arteriosus Constriction and Restrictive Foramen Ovale in d-Transposition of the Great Arteries Circulation, March 9, 1999; 99(9): 1209 - 1214. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Bonnet, A. Coltri, G. Butera, L. Fermont, J. Le Bidois, J. Kachaner, and D. Sidi Detection of Transposition of the Great Arteries in Fetuses Reduces Neonatal Morbidity and Mortality Circulation, February 23, 1999; 99(7): 916 - 918. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Soongswang, I. Adatia, C. Newman, J. F. Smallhorn, W. G. Williams, and R. M. Freedom Mortality in potential arterial switch candidates with transposition of the great arteries J. Am. Coll. Cardiol., September 1, 1998; 32(3): 753 - 757. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Nogi, B. W. McCrindle, C. Boutin, W. G. Williams, R. M. Freedom, and L. N. Benson Fate Of The Neopulmonary Valve After The Arterial Switch Operation In Neonates J. Thorac. Cardiovasc. Surg., March 1, 1998; 115(3): 557 - 562. [Abstract] [Full Text]
|
|
|
|
|
|
G. Wernovsky Follow-up studies after the arterial switch operation J. Thorac. Cardiovasc. Surg., February 1, 1998; 115(2): 481 - 482. [Full Text]
|
|
|
|
|
|
W. G. Williams, J. M. Quaegebeur, J. W. Kirklin, and E. H. Blackstone OUTFLOW OBSTRUCTION AFTER THE ARTERIAL SWITCH OPERATION: A MULTIINSTITUTIONAL STUDY J. Thorac. Cardiovasc. Surg., December 1, 1997; 114(6): 975 - 990. [Abstract] [Full Text]
|
|
|
|
|
|
C. I. Tchervenkov, S. A. Tahta, R. Cecere, and M. J. Beland Single-Stage Arterial Switch With Aortic Arch Enlargement for Transposition Complexes With Aortic Arch Obstruction Ann. Thorac. Surg., December 1, 1997; 64(6): 1776 - 1781. [Abstract] [Full Text]
|
|
|
|
|
|
J. L. Myers Transposition of the Great Arteries Ann. Thorac. Surg., March 1, 1997; 63(3): 895 - 898. [Full Text]
|
|
|
|
|
|
G. B. Luciani, A. C. Chang, and V. A. Starnes Surgical Repair of Transposition of the Great Arteries in Neonates With Persistent Pulmonary Hypertension Ann. Thorac. Surg., March 1, 1996; 61(3): 800 - 804. [Abstract] [Full Text]
|
|
|
|
|
|
K. Turley and E. D Verrier Intermediate Results From the Period of the Congenital Heart Surgeons Transposition Study: 1985 to 1989 Ann. Thorac. Surg., September 1, 1995; 60(3): 505 - 510. [Abstract] [Full Text]
|
|
|
|
|
|
G. Wernovsky, J. E. Mayer Jr., R. A. Jonas, F. L. Hanley, E. H. Blackstone, J. W. Kirklin, and A. R. Castaneda Factors influencing early and late outcome of the arterial switch operation for transposition of the great arteries J. Thorac. Cardiovasc. Surg., February 1, 1995; 109(2): 289 - 302. [Abstract] [Full Text]
|
|
|
|
|
|
W. A. Helbing, B. Hansen, J. Ottenkamp, J. Rohmer, J. G. J. Chin, A. G. Brom, and J. M. Quaegebeur Long-term results of atrial correction for transposition of the great arteries: Comparison of Mustard and Senning operations J. Thorac. Cardiovasc. Surg., August 1, 1994; 108(2): 363 - 372. [Abstract] [Full Text]
|
|
|
|
|
|
M. R. de Leval, K. Francois, C. Bull, W. Brawn, and D. Spiegelhalter Analysis of a cluster of surgical failures: Application to a series of neonatal arterial switch operations J. Thorac. Cardiovasc. Surg., March 1, 1994; 107(3): 914 - 924. [Abstract] [Full Text]
|
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