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(Circulation. 1954;9:581.)
© 1954 American Heart Association, Inc.

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The Origin of Aortic Phospholipid in Rabbit Atheromatosis

D. B. ZILVERSMIT PH.D.¹; MORIS L. SHORE B.A.¹; R. F. ACKERMAN M.D.¹

¹ From the Divisions of Physiology, Preventive Medicine and Medicine, The University of Tennessee College of Medicine, Memphis, Tenn.

Radioactive phosphorus (P³²) was injected into normal and cholesterol-fed rabbits. A marked derangement of aortic phospholipid metabolism was found in the cholesterol-fed animals. The phospholipid found in the atheromatous aortas appeared to have been synthesized by the aorta itself rather than to have been deposited there from the plasma.

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