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(Circulation. 1954;9:706.)
© 1954 American Heart Association, Inc.

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Ventricular Function

I. Starling's Law of the Heart Studied by Means of Simultaneous Right and Left Ventricular Function Curves in the Dog

STANLEY J. SARNOFF M.D.¹ ERIK BERGLUND M.D.¹

¹ From the Department of Physiology, Harvard School of Public Health, Boston, Mass.

Starling's law of the heart has been studied in the dog with a complete circulation with the continuous registration of cardiac output, and atrial and arterial pressures. From this data ventricular function curves were constructed. In any given physiologic state there was a consistent and reproducible correlation between atrial pressure and ventricular stroke work on the same side. The classically conceived descending limb did not occur in the normal heart. The concept of a family of Starling or ventricular function curves adds a third dimension to the adaptive capacity of the heart as put forth by Frank and Starling.

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