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(Circulation. 1995;92:3282-3288.)
© 1995 American Heart Association, Inc.
Articles |
Prolongation of RV-PA Conduit Life Span by Percutaneous Stent Implantation
Intermediate-Term Results
From the Departments of Cardiology (J.E.L., J.F.K., S.B.P.) and Medicine (A.J.P.), Children's Hospital, Harvard Medical School, Boston, Mass.
Background Right ventricle–to–pulmonary artery (RV-PA) homografts and bioprosthetic conduits are commonly used to palliate various types of complex congenital heart disease. These conduits frequently develop progressive obstruction and require surgical replacement. This report reviews our experience implanting balloon-expandable stents to relieve conduit obstruction and delay reoperation.
Methods and Results A retrospective review identified 44 patients
who underwent placement of 48 stents in obstructed RV-PA conduits.
Median patient age was 6.9 years (range, 7 months to 30 years), and
median follow-up time was 14.2 months (range, 0 to 48 months).
Stent implantation initially decreased the RV-PA pressure gradient from
61.0±16.9 to 29.7±11.9 mm Hg (P
.001) and the right
ventricular–to–systemic arterial
pressure ratio from 0.92±0.17 to 0.63±0.20 (P.001).
The
diameter of the stenotic region expanded from 9.3±3.5 to
12.3±3.3 mm in the anteroposterior view (P.001) and from
6.6±2.9 to 10.9±2.5 mm in the lateral view (P.001).
During the follow-up period, 2 patients had their stents redilated,
7 had additional conduit stents deployed, and 14 underwent surgical
replacement of their conduits. Actuarial freedom from conduit
reoperation was 65% at 30 months postprocedure. Seven patients were
found to have fractured stents on follow-up, suggesting an
important role for external compressive forces in conduit failure.
Recatheterization in 16 patients a median of 11.8
months (3 to 48 months) postprocedure demonstrated
hemodynamic evidence of recurrent obstruction despite
sustained enlargement at the previously stented sites. Complications
included stent displacement (n=1), bacterial endocarditis (n=1),
and
false aneurysm formation (n=1). One patient died awaiting
conduit replacement surgery.
Conclusions Stent implantation in obstructed RV-PA conduits results in significant immediate hemodynamic and angiographic improvement. In a subgroup of patients, the procedure prolongs conduit life span by several years and increases the interval between conduit reoperations. Recurrent obstruction is caused by external compression and progressive stenosis outside the stented region.
Key Words: stents • catheterization • heart defects, congenital • angioplasty • prosthesis
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