Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
Circulation. 1995;92:228-232

This Article
Right arrow Full Text
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow Request Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Uemura, H.
Right arrow Articles by Anderson, R. H.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Uemura, H.
Right arrow Articles by Anderson, R. H.

(Circulation. 1995;92:228-232.)
© 1995 American Heart Association, Inc.


Articles

Use of the Bidirectional Glenn Procedure in the Presence of Forward Flow From the Ventricles to the Pulmonary Arteries

Presented at the 67th Scientific Sessions of the American Heart Association, Dallas, Tex, November 1994.

Hideki Uemura, MD; Toshikatsu Yagihara, MD; Yasunaru Kawashima, MD; Kenji Okada, MD; Tetsuro Kamiya, MD; Robert H. Anderson, MD

From the National Cardiovascular Center (H.U., T.Y., Y.K., K.O., T.K.), Suita, Osaka, Japan, and the National Heart and Lung Institute (H.U., R.H.A.), London, UK.

Correspondence to Hideki Uemura, MD, Department of Cardiovascular Surgery, National Cardiovascular Center, 5-7-1 Fujishirodai, Suita, Osaka 565, Japan.

Background Relative regression of the pulmonary arterial size has been reported after a conventional bidirectional Glenn procedure. Maintaining a supplemental pulmonary flow could be of surgical value unless the option also militates against the efficacy of the partial right heart bypass.

Methods and Results Twenty-seven patients considered unsuitable for a Fontan-type procedure underwent a bidirectional Glenn procedure in the presence of forward flow from the ventricles to the pulmonary arteries, the flow being maintained through the pulmonary trunk in 22 or a systemic-to-pulmonary shunt in 5. There was one surgical death due to atrioventricular valvular regurgitation. Subsequently, 9 patients have successfully undergone a total cavopulmonary connection 2.6±1.9 years after the initial procedure. Preoperative and postoperative catheterizations revealed changes in arterial oxygen saturation (75±11% compared with 83±7%, P<.001) and end-diastolic volumes of the systemic ventricles (from 238±92% to 188±97% of the expected normal volume, P<.01), whereas no difference was detected in the mean cross-sectional area of the right and left pulmonary arteries compared with the expected normal value for the right pulmonary artery (from 76±21% to 81±20%) or in the ventricular ejection fraction (from 53±8% to 50±14%). The relative regression or growth of the pulmonary arterial size was statistically related to the size of the channel for forward flow.

Conclusions Maintenance of forward flow from the ventricle provides a feasible means, when performing a bidirectional Glenn procedure, of protecting against regression of pulmonary arterial size as well as off-loading the ventricles and improving arterial oxygen saturation.


Key Words: Glenn procedure • Fontan procedure • surgery • pulmonary arteries • heart defects, congenital




This article has been cited by other articles:


Home page
Ann. Thorac. Surg.Home page
D. F. Calvaruso, A. Rubino, S. Ocello, N. Salviato, D. Guardi, D. F. Petruccelli, A. Cipriani, K. Fattouch, S. Agati, C. Mignosa, et al.
Bidirectional Glenn and Antegrade Pulmonary Blood Flow: Temporary or Definitive Palliation?
Ann. Thorac. Surg., April 1, 2008; 85(4): 1389 - 1396.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
M. Yoshida, M. Yamaguchi, N. Yoshimura, H. Murakami, H. Matsuhisa, and Y. Okita
Appropriate Additional Pulmonary Blood Flow at the Bidirectional Glenn Procedure is Useful for Completion of Total Cavopulmonary Connection
Ann. Thorac. Surg., September 1, 2005; 80(3): 976 - 981.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
S. Shiraishi, H. Uemura, K. Kagisaki, M. Koh, T. Yagihara, and S. Kitamura
The Off-Pump Fontan Procedure by Simply Cross-Clamping the Inferior Caval Vein
Ann. Thorac. Surg., June 1, 2005; 79(6): 2083 - 2088.
[Abstract] [Full Text] [PDF]


Home page
Ann. Thorac. Surg.Home page
D. B. McElhinney, S. M. Marianeschi, and V. M. Reddy
Additional pulmonary blood flow with the bidirectional Glenn anastomosis: does it make a difference?
Ann. Thorac. Surg., August 1, 1998; 66(2): 668 - 672.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Wang, R. S. McLeod, D. A. Gordon, and Z. Yao
The Microsomal Triglyceride Transfer Protein Facilitates Assembly and Secretion of Apolipoprotein B-containing Lipoproteins and Decreases Cotranslational Degradation of Apolipoprotein B in Transfected COS-7 Cells
J. Biol. Chem., June 14, 1996; 271(24): 14124 - 14133.
[Abstract] [Full Text] [PDF]