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(Circulation. 1997;95:376-381.)
© 1997 American Heart Association, Inc.


Articles

Elective Stenting of the Extracranial Carotid Arteries

Jay S. Yadav, MD; Gary S. Roubin, MD, PhD; Sriram Iyer, MD; Jiri Vitek, MD; Peter King, MD; William D. Jordan, MD; Winfield S. Fisher, MD

the Department of Medicine, divisions of Cardiovascular Diseases (J.S.Y., G.S.R., S.I.), Neurology (J.S.Y., P.K.), Radiology (J.V.), Vascular Surgery (W.D.J.), and Neurosurgery (W.S.F.), University of Alabama at Birmingham.

Background Surgical endarterectomy has been shown to be superior to medical management in the management of severe carotid stenosis in both symptomatic and asymptomatic patients. Endarterectomy, although effective, does have limitations, and percutaneous techniques may offer an alternative method of treatment.

Methods and Results The feasibility and safety of percutaneous carotid angioplasty and elective (primary) stenting was evaluated prospectively in a consecutive series of 107 patients. One hundred twenty-six carotid arteries with significant stenosis were treated. This series represented a high-risk subset that included patients with previous ipsilateral endarterectomy and severe medical comorbidity. Forty-five percent of the patients were referred by surgeons. Patients had independent neurological examinations before and after the procedure and follow-up cerebral angiography at 6 months. The mean (±SD) stenosis was reduced from 78±14% to 2±5%. There were 7 minor strokes, 2 major strokes, and 1 death during the initial hospitalization and first 30 days after the procedure. For the combined end point of all strokes and death, the incidence was 7.9%. For ipsilateral major stroke and death, the incidence was 1.6%. There were no strokes during the follow-up period. Mean angiographic stenosis at 6 months in 81 patients was 18±16% (range, -21% to 57%). Four (4.9%) of these 81 patients had asymptomatic restenosis. Five asymptomatic patients had repeat intervention: 2 had angioplasty for restenosis, 2 had angioplasty for stent deformation, and 1 had endarterectomy for restenosis.

Conclusions In a high-risk group of patients, percutaneous carotid angioplasty and stenting are feasible and can be performed with low restenosis and repeat intervention rates.


Key Words: carotid arteries • stents • carotid endarterectomy




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Stroke, August 1, 2001; 32(8): 1855 - 1859.
[Abstract] [Full Text] [PDF]


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CirculationHome page
D. O. Williams
Carotid Filters : New Additions to the Interventionist's Toolbox
Circulation, July 3, 2001; 104(1): 2 - 3.
[Full Text] [PDF]


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StrokeHome page
J.-B. Martin, J.-C. Pache, M. Treggiari-Venzi, K. J. Murphy, P. Gailloud, E. Puget, G. Pizzolato, K. Sugiu, L. Guimaraens, J. Theron, et al.
Role of the Distal Balloon Protection Technique in the Prevention of Cerebral Embolic Events During Carotid Stent Placement
Stroke, February 1, 2001; 32(2): 479 - 484.
[Abstract] [Full Text] [PDF]


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CirculationHome page
G. S. Roubin, G. New, S. S. Iyer, J. J. Vitek, N. Al-Mubarak, M. W. Liu, J. Yadav, C. Gomez, and R. E. Kuntz
Immediate and Late Clinical Outcomes of Carotid Artery Stenting in Patients With Symptomatic and Asymptomatic Carotid Artery Stenosis : A 5-Year Prospective Analysis
Circulation, January 30, 2001; 103(4): 532 - 537.
[Abstract] [Full Text] [PDF]


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StrokeHome page
E. Houdart, C. Mounayer, R. Chapot, J.-P. Saint-Maurice, and J.-J. Merland
Carotid Stenting for Radiation-Induced Stenoses : A Report of 7 Cases
Stroke, January 1, 2001; 32(1): 118 - 121.
[Abstract] [Full Text] [PDF]


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ANGIOLOGYHome page
T. J. Tegos, E. Kalodiki, and A. N. Nicolaides
Stroke: Management and Rehabilitation: Part III of III
Angiology, December 1, 2000; 51(12): 977 - 984.
[Abstract] [PDF]


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StrokeHome page
A. M. Malek, R. T. Higashida, C. C. Phatouros, T. E. Lempert, P. M. Meyers, W. S. Smith, C. F. Dowd, and V. V. Halbach
Stent Angioplasty for Cervical Carotid Artery Stenosis in High-Risk Symptomatic NASCET-Ineligible Patients
Stroke, December 1, 2000; 31(12): 3029 - 3033.
[Abstract] [Full Text] [PDF]


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Am. J. Neuroradiol.Home page
W. Morrish, S. Grahovac, A. Douen, G. Cheung, W. Hu, R. Farb, P. Kalapos, R. Wee, M. Hudon, C. Agbi, et al.
Intracranial Hemorrhage after Stenting and Angioplasty of Extracranial Carotid Stenosis
AJNR Am. J. Neuroradiol., November 1, 2000; 21(10): 1911 - 1916.
[Abstract] [Full Text] [PDF]


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RadiologyHome page
C. C. Phatouros, R. T. Higashida, A. M. Malek, P. M. Meyers, T. E. Lempert, C. F. Dowd, and V. V. Halbach
Carotid Artery Stent Placement for Atherosclerotic Disease: Rationale, Technique, and Current Status
Radiology, October 1, 2000; 217(1): 26 - 41.
[Abstract] [Full Text]


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J Am Coll CardiolHome page
F. Shawl, W. Kadro, M. J. Domanski, F. L. Lapetina, A. A. Iqbal, K. G. Dougherty, D. D. Weisher, J. F. Marquez, and S. T. Shahab
Safety and efficacy of elective carotid artery stenting in high-risk patients
J. Am. Coll. Cardiol., June 1, 2000; 35(7): 1721 - 1728.
[Abstract] [Full Text] [PDF]


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RadiologyHome page
G. Dangas, J. R. Laird Jr, L. F. Satler, R. Mehran, G. S. Mintz, G. Larrain, A. J. Lansky, L. Gruberg, E. M. Parsons, R. Laureno, et al.
Postprocedural Hypotension after Carotid Artery Stent Placement: Predictors and Short- and Long-term Clinical Outcomes
Radiology, June 1, 2000; 215(3): 677 - 683.
[Abstract] [Full Text]


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StrokeHome page
J. Golledge, A. Mitchell, R. M. Greenhalgh, and A. H. Davies
Systematic Comparison of the Early Outcome of Angioplasty and Endarterectomy for Symptomatic Carotid Artery Disease
Stroke, June 1, 2000; 31(6): 1439 - 1443.
[Abstract] [Full Text] [PDF]


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Am. J. Neuroradiol.Home page
C. R. Gomez, V. K. Misra, M. S. Campbell, and R. D. Soto
Elective Stenting of Symptomatic Middle Cerebral Artery Stenosis
AJNR Am. J. Neuroradiol., May 1, 2000; 21(5): 971 - 973.
[Abstract] [Full Text]


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CMAJHome page
Carotid angioplasty and stenting: current status
Can. Med. Assoc. J., May 1, 2000; 162(10): 1451 - 1454.



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Am. J. Neuroradiol.Home page
C. C. Phatouros, R. T. Higashida, A. M. Malek, P. M. Meyers, T. E. Lempert, C. F. Dowd, and V. V. Halbach
Endovascular Stenting for Carotid Artery Stenosis: Preliminary Experience Using the Shape-memory-Alloy-recoverable-technology (SMART) Stent
AJNR Am. J. Neuroradiol., April 1, 2000; 21(4): 732 - 738.
[Abstract] [Full Text]


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StrokeHome page
I. D. Wilkinson, P. D. Griffiths, N. Hoggard, T. J. Cleveland, P. A. Gaines, and G. S. Venables
Unilateral Leptomeningeal Enhancement After Carotid Stent Insertion Detected by Magnetic Resonance Imaging
Stroke, April 1, 2000; 31(4): 848 - 851.
[Abstract] [Full Text] [PDF]


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Am. J. Neuroradiol.Home page
J. J. Connors III, D. Seidenwurm, J. C. Wojak, R. W. Hurst, M. E. Jensen, R. Wallace, T. Tomsick, J. Barr, C. Kerber, E. Russell, et al.
Treatment of Atherosclerotic Disease at the Cervical Carotid Bifurcation: Current Status and Review of the Literature
AJNR Am. J. Neuroradiol., March 1, 2000; 21(3): 444 - 450.
[Full Text]


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CirculationHome page
E. J. Topol and J. S. Yadav
Recognition of the Importance of Embolization in Atherosclerotic Vascular Disease
Circulation, February 8, 2000; 101(5): 570 - 580.
[Full Text] [PDF]


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StrokeHome page
C. R. Gomez, V. K. Misra, M. W. Liu, V. R. Wadlington, J. B. Terry, R. Tulyapronchote, and M. S. Campbell
Elective Stenting of Symptomatic Basilar Artery Stenosis
Stroke, January 1, 2000; 31(1): 95 - 99.
[Abstract] [Full Text] [PDF]


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StrokeHome page
D. J. H. McCabe, M. M. Brown, and A. Clifton
Fatal Cerebral Reperfusion Hemorrhage After Carotid Stenting
Stroke, November 1, 1999; 30 (11): 2483 - 2486.
[Abstract] [Full Text] [PDF]


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Am. J. Neuroradiol.Home page
P. P. Morris, E. M. Martin, J. Regan, and G. Braden
Intracranial Deployment of Coronary Stents for Symptomatic Atherosclerotic Disease
AJNR Am. J. Neuroradiol., October 1, 1999; 20(9): 1688 - 1694.
[Abstract] [Full Text]


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StrokeHome page
A. M. Malek, R. T. Higashida, C. C. Phatouros, T. E. Lempert, P. M. Meyers, D. R. Gress, C. F. Dowd, and V. V. Halbach
Treatment of Posterior Circulation Ischemia With Extracranial Percutaneous Balloon Angioplasty and Stent Placement
Stroke, October 1, 1999; 30(10): 2073 - 2085.
[Abstract] [Full Text] [PDF]


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StrokeHome page
A. I. Qureshi, A. R. Luft, M. Sharma, V. Janardhan, D. K. Lopes, J. Khan, L. R. Guterman, and L. N. Hopkins
Frequency and Determinants of Postprocedural Hemodynamic Instability After Carotid Angioplasty and Stenting
Stroke, October 1, 1999; 30(10): 2086 - 2093.
[Abstract] [Full Text] [PDF]


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Am. J. Neuroradiol.Home page
T. Mori, K. Kazita, T. Mima, and K. Mori
Balloon Angioplasty for Embolic Total Occlusion of the Middle Cerebral Artery and Ipsilateral Carotid Stenting in an Acute Stroke Stage
AJNR Am. J. Neuroradiol., September 1, 1999; 20(8): 1462 - 1464.
[Abstract] [Full Text]


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RadiologyHome page
H. I. Manninen, H. T. Räsänen, R. L. Vanninen, P. Vainio, M. Hippeläinen, and V.-M. Kosma
Stent Placement versus Percutaneous Transluminal Angioplasty of Human Carotid Arteries in Cadavers in Situ: Distal Embolization and Findings at Intravascular US, MR Imaging, and Histopathologic Analysis
Radiology, August 1, 1999; 212(2): 483 - 492.
[Abstract] [Full Text]


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Ann. Thorac. Surg.Home page
G. Babatasi, M. Massetti, and J. Theron
Coexistent coronary and cerebrovascular disease: a place for carotid stenting
Ann. Thorac. Surg., July 1, 1999; 68(1): 297 - 297.
[Full Text] [PDF]


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Am. J. Neuroradiol.Home page
Mori, Kazita, and Mori
Cerebral Angioplasty and Stenting for Intracranial Vertebral Atherosclerotic
AJNR Am. J. Neuroradiol., May 1, 1999; 20(5): 787 - 789.
[Abstract] [Full Text]


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StrokeHome page
M. P. Marks, M. Marcellus, A. M. Norbash, G. K. Steinberg, D. Tong, and G. W. Albers
Outcome of Angioplasty for Atherosclerotic Intracranial Stenosis
Stroke, May 1, 1999; 30(5): 1065 - 1069.
[Abstract] [Full Text] [PDF]


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J Am Coll CardiolHome page
P. Hadjipetrou, S. Cox, T. Piemonte, and A. Eisenhauer
Percutaneous revascularization of atherosclerotic obstruction of aortic arch vessels
J. Am. Coll. Cardiol., April 1, 1999; 33(5): 1238 - 1245.
[Abstract] [Full Text] [PDF]


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VASC ENDOVASCULAR SURGHome page
M. R. Lepore, W. D. Jordan Jr, W. S. Fisher, D. C. Voellinger, D. Redden, and H. A. McDowell
Treatment of Recurrent Carotid Stenosis: Angioplasty with Stenting versus Reoperative Carotid Surgery
Vascular and Endovascular Surgery, November 1, 1998; 32(6): 523 - 530.
[Abstract] [PDF]


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StrokeHome page
J. T. Robertson
Carotid Endarterectomy: A Saga of Clinical Science, Personalities, and Evolving Technology : The Willis Lecture
Stroke, November 1, 1998; 29(11): 2435 - 2441.
[Full Text] [PDF]


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CirculationHome page
G. Dorros
Stent-Supported Carotid Angioplasty : Should It Be Done, and, If So, by Whom? A 1998 Perspective
Circulation, September 1, 1998; 98(9): 927 - 930.
[Full Text] [PDF]


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Am. J. Neuroradiol.Home page
G. S. Roubin
Dear Editor-in-Chief:
AJNR Am. J. Neuroradiol., August 1, 1998; 20(7): 1378 - 1381.
[Full Text]


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CirculationHome page
A. Mathur, G. S. Roubin, S. S. Iyer, C. Piamsonboon, M. W. Liu, C. R. Gomez, J. S. Yadav, H. D. Chastain, L. M. Fox, L. S. Dean, et al.
Predictors of Stroke Complicating Carotid Artery Stenting
Circulation, April 7, 1998; 97(13): 1239 - 1245.
[Abstract] [Full Text] [PDF]