Donate Help Contact The AHA Sign In Home
American Heart Association
Circulation
Search: search_blue_button Advanced Search
Circulation. 1999;100:1132-1133

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowRequest Permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Related Collections
Right arrow Primary prevention
Right arrow Risk Factors
Right arrow Chronic ischemic heart disease

(Circulation. 1999;100:1132-1133.)
© 1999 American Heart Association, Inc.


Joint Editorial Statement

Diabetes Mellitus: A Major Risk Factor for Cardiovascular Disease

A Joint Editorial Statement by the American Diabetes Association; the National Heart, Lung, and Blood Institute; the Juvenile Diabetes Foundation International; the National Institute of Diabetes and Digestive and Kidney Diseases; and the American Heart Association


Key Words: AHA Scientific Statements • diabetes mellitus • risk factors • cardiovascular diseases


*    Introduction
 
Abundant evidence shows that patients with type 1 diabetes or type 2 diabetes are at high risk for several cardiovascular disorders: coronary heart disease, stroke, peripheral arterial disease, cardiomyopathy, and congestive heart failure. Cardiovascular complications are now the leading causes of diabetes-related morbidity and mortality. The public health impact of cardiovascular disease (CVD) in patients with diabetes is already enormous and is increasing. Several explanations are behind this increase. First, the incidence of diabetes rises with advancing age, and the number of older people in the United States is growing rapidly. Second, insulin treatment for persons with type 1 diabetes has prolonged their lives significantly, and with each year of additional life comes an increased risk for CVD complications. Third, type 2 diabetes occurs at an earlier age in obese and overweight persons, and the prevalence of obesity is rising in the United States. The risk for diabetes in overweight persons is heightened by physical inactivity; unfortunately, the majority of Americans engage in little regular or sustained physical activity. Fourth, the populations that are particularly susceptible to diabetes—African Americans, Hispanics, Native Americans, Pacific Islanders, and Asiansare growing in this country. Fifth, improved medical care, particularly when extended to susceptible populations, will bring an increasing number of patients with type 2 diabetes into the medical care system. All of these factors will lead to an absolute increase in the number of patients who will require medical intervention to prevent the complications of diabetes.

Diabetes has long been recognized to . . . [Full Text of this Article]




This article has been cited by other articles:


Home page
J Am Coll CardiolHome page
D. Aguilar, B. Bozkurt, K. Ramasubbu, and A. Deswal
Relationship of hemoglobin A1C and mortality in heart failure patients with diabetes.
J. Am. Coll. Cardiol., July 28, 2009; 54(5): 422 - 428.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
L. A. Lesniewski, A. J. Donato, B. J. Behnke, C. R. Woodman, M. H. Laughlin, C. A. Ray, and M. D. Delp
Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension
Am J Physiol Heart Circ Physiol, April 1, 2008; 294(4): H1840 - H1850.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
J. B. Buse, H. N. Ginsberg, G. L. Bakris, N. G. Clark, F. Costa, R. Eckel, V. Fonseca, H. C. Gerstein, S. Grundy, R. W. Nesto, et al.
Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus: A Scientific Statement From the American Heart Association and the American Diabetes Association
Circulation, January 2, 2007; 115(1): 114 - 126.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
J. B. Buse, H. N. Ginsberg, G. L. Bakris, N. G. Clark, F. Costa, R. Eckel, V. Fonseca, H. C. Gerstein, S. Grundy, R. W. Nesto, et al.
Primary Prevention of Cardiovascular Diseases in People With Diabetes Mellitus: A scientific statement from the American Heart Association and the American Diabetes Association
Diabetes Care, January 1, 2007; 30(1): 162 - 172.
[Abstract] [Full Text] [PDF]


Home page
Eur Heart JHome page
S. Ahmed, C. P. Cannon, S. A. Murphy, and E. Braunwald
Acute coronary syndromes and diabetes: is intensive lipid lowering beneficial? Results of the PROVE IT-TIMI 22 trial
Eur. Heart J., October 1, 2006; 27(19): 2323 - 2329.
[Abstract] [Full Text] [PDF]


Home page
BMJHome page
J. Costa, M. Borges, C. David, and A. Vaz Carneiro
Efficacy of lipid lowering drug treatment for diabetic and non-diabetic patients: meta-analysis of randomised controlled trials
BMJ, May 13, 2006; 332(7550): 1115 - 1124.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
S. M. Grundy
Metabolic Syndrome: Connecting and Reconciling Cardiovascular and Diabetes Worlds
J. Am. Coll. Cardiol., March 21, 2006; 47(6): 1093 - 1100.
[Abstract] [Full Text] [PDF]


Home page
J Trop PediatrHome page
S. Abdelghaffar, M. El Amir, A. El Hadidi, and F. El Mougi
Carotid Intima-Media Thickness: An Index for Subclinical Atherosclerosis in Type 1 Diabetes
J Trop Pediatr, February 1, 2006; 52(1): 39 - 45.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
P. Raggi, A. Bellasi, and C. Ratti
Ischemia Imaging and Plaque Imaging in Diabetes: Complementary tools to improve cardiovascular risk management
Diabetes Care, November 1, 2005; 28(11): 2787 - 2794.
[Abstract] [Full Text] [PDF]


Home page
Am J Health Syst PharmHome page
M. W. Strum, R. Hopkins, D. S. West, and B. N. Harris
Effects of a medication assistance program on health outcomes in patients with type 2 diabetes mellitus
Am. J. Health Syst. Pharm., May 15, 2005; 62(10): 1048 - 1052.
[Abstract] [Full Text] [PDF]


Home page
RadiologyHome page
M. Venturini, E. Angeli, P. Maffi, P. Fiorina, F. Bertuzzi, M. Salvioni, F. De Cobelli, C. Socci, L. Aldrighetti, C. Losio, et al.
Technique, Complications, and Therapeutic Efficacy of Percutaneous Transplantation of Human Pancreatic Islet Cells in Type 1 Diabetes: The Role of US
Radiology, February 1, 2005; 234(2): 617 - 624.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
D. Aguilar, S. D. Solomon, L. Kober, J.-L. Rouleau, H. Skali, J. J.V. McMurray, G. S. Francis, M. Henis, C. M. O'Connor, R. Diaz, et al.
Newly Diagnosed and Previously Known Diabetes Mellitus and 1-Year Outcomes of Acute Myocardial Infarction: The Valsartan in Acute Myocardial Infarction (VALIANT) Trial
Circulation, September 21, 2004; 110(12): 1572 - 1578.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
P. Fiorina, F. Folli, A. D'Angelo, G. Finzi, F. Pellegatta, V. Guzzi, C. Fedeli, P. D. Valle, L. Usellini, C. Placidi, et al.
Normalization of Multiple Hemostatic Abnormalities in Uremic Type 1 Diabetic Patients After Kidney-Pancreas Transplantation
Diabetes, September 1, 2004; 53(9): 2291 - 2300.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
B. Charbonnel, J. Dormandy, E. Erdmann, M. Massi-Benedetti, and A. Skene
The Prospective Pioglitazone Clinical Trial in Macrovascular Events (PROactive): Can pioglitazone reduce cardiovascular events in diabetes? Study design and baseline characteristics of 5,238 patients
Diabetes Care, July 1, 2004; 27(7): 1647 - 1653.
[Abstract] [Full Text] [PDF]


Home page
Arch Intern MedHome page
R. W. Grant, P. A. Pirraglia, J. B. Meigs, and D. E. Singer
Trends in Complexity of Diabetes Care in the United States From 1991 to 2000
Arch Intern Med, May 24, 2004; 164(10): 1134 - 1139.
[Abstract] [Full Text] [PDF]


Home page
American Journal of Medical QualityHome page
D. Fetterolf and R. West
The Business Case for Quality: Combining Medical Literature Research with Health Plan Data to Establish Value for Nonclinical Managers
American Journal of Medical Quality, March 1, 2004; 19(2): 48 - 55.
[Abstract] [PDF]


Home page
Biol Res NursHome page
E. R. Chasens, T. E. Weaver, and M. G. Umlauf
Insulin Resistance and Obstructive Sleep Apnea: Is Increased Sympathetic Stimulation the Link?
Biol Res Nurs, October 1, 2003; 5(2): 87 - 96.
[Abstract] [PDF]


Home page
J Am Coll CardiolHome page
Committee Members, F. J. Klocke, M. G. Baird, B. H. Lorell, T. M. Bateman, J. V. Messer, D. S. Berman, P. T. O'Gara, B. A. Carabello, R. O. Russell Jr, et al.
ACC/AHA/ASNC Guidelines for the Clinical Use of Cardiac Radionuclide Imaging--Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuclide Imaging)
J. Am. Coll. Cardiol., October 1, 2003; 42(7): 1318 - 1333.
[Full Text] [PDF]


Home page
Diabetes CareHome page
A. Keech, D. Colquhoun, J. Best, A. Kirby, R. J. Simes, D. Hunt, W. Hague, E. Beller, M. Arulchelvam, J. Baker, et al.
Secondary Prevention of Cardiovascular Events With Long-Term Pravastatin in Patients With Diabetes or Impaired Fasting Glucose: Results from the LIPID trial
Diabetes Care, October 1, 2003; 26(10): 2713 - 2721.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
F. J. Klocke, M. G. Baird, B. H. Lorell, T. M. Bateman, J. V. Messer, D. S. Berman, P. T. O'Gara, B. A. Carabello, R. O. Russell Jr, M. D. Cerqueira, et al.
ACC/AHA/ASNC Guidelines for the Clinical Use of Cardiac Radionuclide Imaging--Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuclide Imaging)
Circulation, September 16, 2003; 108(11): 1404 - 1418.
[Full Text] [PDF]


Home page
Diabetes CareHome page
R. W. Grant, H. E. Hamrick, C. M. Sullivan, A. K. Dubey, H. C. Chueh, E. Cagliero, and J. B. Meigs
Impact of Population Management With Direct Physician Feedback on Care of Patients With Type 2 Diabetes
Diabetes Care, August 1, 2003; 26(8): 2275 - 2280.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
P. Fiorina, F. Folli, F. Bertuzzi, P. Maffi, G. Finzi, M. Venturini, C. Socci, A. Davalli, E. Orsenigo, L. Monti, et al.
Long-Term Beneficial Effect of Islet Transplantation on Diabetic Macro-/Microangiopathy in Type 1 Diabetic Kidney-Transplanted Patients
Diabetes Care, April 1, 2003; 26(4): 1129 - 1136.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
L. E. Eberly, J. D. Cohen, R. Prineas, and L. Yang
Impact of Incident Diabetes and Incident Nonfatal Cardiovascular Disease on 18-Year Mortality: The Multiple Risk Factor Intervention Trial experience
Diabetes Care, March 1, 2003; 26(3): 848 - 854.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
B. Ryerson, E. F. Tierney, T. J. Thompson, M. M. Engelgau, J. Wang, E. W. Gregg, and L. S. Geiss
Excess Physical Limitations Among Adults With Diabetes in the U.S. Population, 1997-1999
Diabetes Care, January 1, 2003; 26(1): 206 - 210.
[Abstract] [Full Text] [PDF]


Home page
DiabetesHome page
P. Iozzo, P. Chareonthaitawee, D. Dutka, D. J. Betteridge, E. Ferrannini, and P. G. Camici
Independent Association of Type 2 Diabetes and Coronary Artery Disease With Myocardial Insulin Resistance
Diabetes, October 1, 2002; 51(10): 3020 - 3024.
[Abstract] [Full Text] [PDF]


Home page
The Diabetes EducatorHome page
E. R. Chasens, M. Q. Umlauf, D. J. Pillion, and J. A. Wells
Nocturnal Polyuria in Type 2 Diabetes: A Symptom of Obstructive Sleep Apnea
The Diabetes Educator, May 1, 2002; 28(3): 424 - 434.
[Abstract] [PDF]


Home page
Arch Intern MedHome page
L. E. Egede and D. Zheng
Modifiable Cardiovascular Risk Factors in Adults With Diabetes: Prevalence and Missed Opportunities for Physician Counseling
Arch Intern Med, February 25, 2002; 162(4): 427 - 433.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
F. J. Th. Wackers and B. L. Zaret
Detection of Myocardial Ischemia in Patients With Diabetes Mellitus
Circulation, January 1, 2002; 105(1): 5 - 7.
[Full Text] [PDF]


Home page
CirculationHome page
S. C. Smith Jr, S. N. Blair, R. O. Bonow, L. M. Brass, M. D. Cerqueira, K. Dracup, V. Fuster, A. Gotto, S. M. Grundy, N. H. Miller, et al.
AHA/ACC Guidelines for Preventing Heart Attack and Death in Patients With Atherosclerotic Cardiovascular Disease: 2001 Update: A Statement for Healthcare Professionals From the American Heart Association and the American College of Cardiology
Circulation, September 25, 2001; 104(13): 1577 - 1579.
[Full Text] [PDF]


Home page
DiabetesHome page
P. Fiorina, E. La Rocca, M. Venturini, F. Minicucci, I. Fermo, R. Paroni, A. D’Angelo, M. Sblendido, V. Di Carlo, M. Cristallo, et al.
Effects of Kidney-Pancreas Transplantation on Atherosclerotic Risk Factors and Endothelial Function in Patients With Uremia and Type 1 Diabetes
Diabetes, March 1, 2001; 50(3): 496 - 501.
[Abstract] [Full Text]


Home page
HeartHome page
G. S FRANCIS
Diabetic cardiomyopathy: fact or fiction?
Heart, March 1, 2001; 85(3): 247 - 248.
[Full Text]


Home page
Diabetes CareHome page
S. Schurgin, S. Rich, and T. Mazzone
Increased Prevalence of Significant Coronary Artery Calcification in Patients With Diabetes
Diabetes Care, February 1, 2001; 24(2): 335 - 338.
[Abstract] [Full Text]


Home page
Arch Intern MedHome page
J. A. D'Elia, L. A. Weinrauch, R. E. Gleason, I. Lipinska, J. Keough, S. Pendse, B. Roshan, A. T. Lee, and G. H. Tofler
Fibrinogen and Factor VII Levels Improve With Glycemic Control in Patients With Type 1 Diabetes Mellitus Who Have Microvascular Complications
Arch Intern Med, January 8, 2001; 161(1): 98 - 101.
[Abstract] [Full Text] [PDF]


Home page
Diabetes CareHome page
S. A. Grover, L. Coupal, H. Zowall, C. M. Alexander, T. W. Weiss, and D. R.J. Gomes
How Cost-Effective Is the Treatment of Dyslipidemia in Patients With Diabetes but Without Cardiovascular Disease?
Diabetes Care, January 1, 2001; 24(1): 45 - 50.
[Abstract] [Full Text]


Home page
CirculationHome page
S. M. Grundy, T. Bazzarre, J. Cleeman, R. B. D’Agostino Sr, M. Hill, N. Houston-Miller, W. B. Kannel, R. Krauss, H. M. Krumholz, R. M. Lauer, et al.
Prevention Conference V : Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Medical Office Assessment : Writing Group I
Circulation, January 4, 2000; 101 (1): e3 - e11.
[Full Text] [PDF]