(Circulation. 2000;101:e28.)
© 2000 American Heart Association, Inc.
Circulation Electronic Pages |
1 Circulation Newswriter
| Introduction |
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"Although the potential for the fields of molecular biology and genetics to improve identification of persons and populations at risk, to predict the evolution of a disease in a specific patient, and to optimize pharmacological intervention is exciting and worthy of pursuit, physicians must not lose sight of perhaps more mundane but clearly effective approaches such as lowering blood pressure, reducing obesity and physical inactivity, and applying other proven therapeutic strategies (eg, ß-blockers, aspirin) in a timely fashion," said Dr Lenfant.
In his editorial, Dr Lenfant said he thinks the field of
cardiology is on the cusp of new findings that will
prove important in the understanding of
atherosclerosis. "On the eve of the next millennium,
it is safe to predict that the importance and application of molecular
genetics and functional genomics will play major roles in the further
improvement of cardiovascular health." He praised
research such as that published in the special
cardiovascular-themed issue of the Journal of the
American Medical Association that appeared on December 1.
"However, translation of these research results into lifestyle
changes, public health interventions, and clinical practice, remains a
major challenge. Experts and public health advocates decry with alarm
the cardiovascular health status of the populace,
particularly regarding obesity, physical
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