(Circulation. 2000;102:IV-58.)
© 2000 American Heart Association, Inc.
Special Anniversary Issue |
From the Division of Cardiology, Department of Pediatrics, the Hospital for Sick Children and University of Toronto Faculty of Medicine (R.M.F.); the Department of Cardiology, the Childrens Hospital and Harvard Medical School, Boston (J.L.); and the Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics, Baylor College of Medicine and Texas Childrens Hospital, Houston, Tex (J.T.B.).
Correspondence to Robert M. Freedom, MD, The Hospital for Sick Children, 555 University Ave, Room 1503, Toronto, Ontario, Canada M5G 1X8. E-mail rfreedom@sickkids.on.ca
Key Words: defects Fontan procedure pediatrics prostaglandins transposition of great vessels
For those caring for the patient with
congenital heart disease, the last 50 years of the 20th century was
witness to staggering advances in virtually all aspects of pediatric
cardiovascular medicine and surgery. The first half of the 20th century
was not dormant in this regard. Dr Maude Abbott of Montreal had
published her wonderful atlas in 1936 under the auspices of the
American Heart Association, a unique compilation of 1000 cases of
congenital heart
disease.1 Dr Helen
Taussig of Baltimore had founded her cardiac clinic at Johns Hopkins
and had begun in the 1930s to characterize the clinical and
fluoroscopic findings of a wide variety of congenital heart
malformations; this material matured into her 2-volume compendium on
congenital heart disease published in
1960.2 Dr Robert E.
Gross of the Childrens Hospital in Boston successfully ligated the
patent arterial duct in 1938, and that signal accomplishment ushered in
the era of surgery for congenital heart
disease.3 On the
basis of her clinical observations that some children with cyanotic
congenital heart disease became progressively more cyanotic
coincidently with closure of the arterial duct and cognizant of
Grosss benchmark contribution, Dr Taussig traveled to Boston to
attempt to persuade him to construct an arterial duct. When he refused,
she broached the subject to Dr Blalock at Johns Hopkins. Some years
earlier, when in Vanderbilt and with the technical assistance of Vivien
Thomas, in an attempt to produce pulmonary hypertension and using the
dog as the experimental animal, Dr Blalock constructed an end-to-end
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