This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Related Collections Related Articles

(Circulation. 2004;110:1177.)
© 2004 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

PREVALENT LOW-FREQUENCY OSCILLATION OF HEART RATE: NOVEL PREDICTOR OF MORTALITY AFTER MYOCARDIAL INFARCTION, by Wichterle et al.

Risk stratification after myocardial infarction is of interest to guide the use of effective but costly additional therapy. Noninvasive markers, including diminished heart rate variability (HRV), have limited predictive accuracy and have not been widely adopted. This study reports a novel HRV analysis that defines the prevalent low-frequency oscillation (PLF) in the low-frequency (0.05 to 0.15 Hz) range. Tested retrospectively in two large, independent multicenter trials, PLF in the high end of this spectral range was associated with a >4-fold increase in mortality. PLF was not correlated with several other HRV measures, which suggests that it may reflect different phenomena than those reflected in available tests. These methods offer potential insight into noninvasive risk stratification after myocardial infarction. See p 1183.

IMPACT OF THE METABOLIC SYNDROME ON MORTALITY FROM CORONARY HEART DISEASE, CARDIOVASCULAR DISEASE, AND ALL CAUSES IN UNITED STATES ADULTS, by Malik et al.

It is estimated that 24% of the US population has the metabolic syndrome. Whereas the high mortality rate associated with diabetes itself is established, the mortality rate associated with the metabolic syndrome has been less well understood. The investigators examined data from the US Second National Health and Nutrition Examination Survey and noted that the metabolic syndrome was associated with a doubling in coronary heart disease mortality. Compared with individuals who had neither the metabolic syndrome nor prior cardiovascular disease, those with the metabolic syndrome had a 40% increased risk of dying. Moreover, the investigators noted that the metabolic syndrome more strongly predicted coronary heart, cardiovascular, and total mortality than its individual components. In that the obesity epidemic in the United States has led to a rise in . . . [Full Text of this Article]

Related Articles:

Impact of the Metabolic Syndrome on Mortality From Coronary Heart Disease, Cardiovascular Disease, and All Causes in United States Adults

Shaista Malik, Nathan D. Wong, Stanley S. Franklin, Tripthi V. Kamath, Gilbert J. L’Italien, Jose R. Pio, and G. Rhys Williams
Circulation 2004 110: 1245-1250. [Abstract] [Full Text]

Simvastatin Induces Heme Oxygenase-1: A Novel Mechanism of Vessel Protection

Tzong-Shyuan Lee, Chih-Chieh Chang, Yi Zhu, and John Y.-J. Shyy
Circulation 2004 110: 1296-1302. [Abstract] [Full Text]

Prevalent Low-Frequency Oscillation of Heart Rate: Novel Predictor of Mortality After Myocardial Infarction

Dan Wichterle, Jan Simek, Maria Teresa La Rovere, Peter J. Schwartz, A. John Camm, and Marek Malik
Circulation 2004 110: 1183-1190. [Abstract] [Full Text]

Multiple Radial Artery Plaques

Takatoshi Wakeyama, Hiroshi Ogawa, Takahiro Iwami, Kyonori Yasumoto, and Masunori Matsuzaki
Circulation 2004 110: e293-e294. [Extract] [Full Text]

Multimodality Imaging of Hemangiectasia Hypertrophicans (Klippel-Trenaunay-Parkes-Weber Syndrome)

Robert A. Bucek, Joachim Vavrik, Erich Minar, Johannes Lammer, and Dimiter Tscholakoff
Circulation 2004 110: e295. [Extract] [Full Text]