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(Circulation. 2005;111:3185.)
© 2005 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	HYPOTHERMIA IMPROVES DEFIBRILLATION SUCCESS AND RESUSCITATION OUTCOMES FROM VENTRICULAR FIBRILLATION, by Boddicker et al.

 
Mild hypothermia (32°C to 35°C) improves neurological outcome in patients with coma after resuscitation from ventricular fibrillation. However, hypothermia itself can cause ventricular fibrillation, and its implementation is believed to be contraindicated when life-threatening arrhythmias continue. This study examined the effects of hypothermia on restoration of circulation after 8 minutes of ventricular fibrillation in swine. Hypothermia implemented before arrest improved the success of defibrillation and resuscitation. These findings suggest that, in addition to neurological benefits, hypothermia may have cardiac benefits in some situations. Further studies of hypothermia during cardiac arrest are warranted. See p 3195.

	IMPACT OF PROSTHESIS–PATIENT SIZE ON FUNCTIONAL RECOVERY AFTER AORTIC VALVE REPLACEMENT, by Koch et al.

 
Functional recovery after aortic valve replacement is a key goal in addition to informed survival. Controversy remains with regard to the impact of a small-sized prosthesis implanted into a large and physically active patient. This study of more than 1000 patients early after aortic valve replacement documents similar functional recovery for the full spectrum of aortic valve sizes indexed to the body size of the patient. These data suggest that factors other than prosthesis-patient mismatch may be responsible for the adverse influences on functional recovery and quality of life. See p 3221.

	MAGNITUDE OF AND RISK FACTORS FOR IN-HOSPITAL AND POSTDISCHARGE STROKE IN PATIENTS WITH ACUTE CORONARY SYNDROMES: FINDINGS FROM A GLOBAL REGISTRY OF ACUTE CORONARY EVENTS, by Budaj et al.

 
This report by Budaj et al involves 35 233 patients with an acute coronary syndrome (ACS) admitted to 94 hospitals in 14 countries between April 1999 and December 2003 as part of the GRACE Registry. A total of 579 patients (1.6%) experienced a stroke between hospital admission and 6 months after discharge (310 in hospital; 269 after discharge). Risk factors for . . . [Full Text of this Article]

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