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(Circulation. 2006;114:1897.)
© 2006 American Heart Association, Inc.

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An extract of the first 250 words of the full text is provided, because this article has no abstract.

	PRESENCE OF A VENTRICULAR SEPTAL DEFECT AND THE MUSTARD OPERATION ARE RISK FACTORS FOR LATE MORTALITY AFTER THE ATRIAL SWITCH OPERATION: THIRTY YEARS OF FOLLOW-UP IN 417 PATIENTS AT A SINGLE CENTER, by Lange et al.

 
Many patients with transposition of the great vessels are surviving for decades after surgical repair. For decades, the surgical approach to transposition of the great vessels had been an atrial switch (Senning or Mustard) procedure. Currently, an arterial switch is the standard preferred procedure. The late results of procedures that are not in vogue today, however, are of importance in caring for the growing population of adults with repaired congenital cardiac defects. This study by Lange et al, from a single center, reviews 329 patients after a Senning Procedure and 88 after a Mustard operation with mean follow-up of 19 years. This historic collective of the atrial switch operations, especially those that require ventricular septal defect closure, provides the clinician with information about how to advise and follow this patient population. See p 1905.

	PERIPHERAL ARTERIAL DISEASE IN PATIENTS WITH END-STAGE RENAL DISEASE: OBSERVATIONS FROM THE DIALYSIS OUTCOMES AND PRACTICE PATTERNS STUDY (DOPPS), by Rajagopalan et al.

 
Patients with end-stage renal disease and patients with peripheral arterial disease are both at high risk for cardiovascular morbidity and mortality. In Rajagopalan and colleagues examined a large international cohort of hemodialysis patients to understand the prevalence and prognosis of peripheral arterial disease in hemodialysis patients. Although they observed significant international variation, the investigators report a poor prognosis in the 25% of patients with peripheral arterial disease. Their research revealed an approximately 40% increased risk of cardiac and all-cause mortality and a doubling of cardiovascular events in hemodialysis patients, who already experience significant risk because of their end-stage kidney disease. The present study provides support for efforts to understand how to prevent the progression of . . . [Full Text of this Article]

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