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(Circulation. 2007;115:1333.)
© 2007 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	ASSOCIATION OF PLASMA NATRIURETIC PEPTIDE LEVELS WITH METABOLIC RISK FACTORS IN AMBULATORY INDIVIDUALS, by Wang et al.

 
The metabolic syndrome, comprising obesity, glucose intolerance, dyslipidemia, hypertension, and insulin resistance, is associated with a high risk of cardiovascular disease. Several studies have shown that obesity is associated with low levels of B-type natriuretic peptides (BNP), which, in turn, have been shown to be an adverse risk factor in a number of cardiac conditions. In this issue of Circulation, Wang and colleagues show, in 3333 Framingham subjects without heart failure, that BNP levels were inversely associated with all components of the metabolic syndrome except hypertension. Although these data cannot determine which came first, the low BNP or the metabolic syndrome, the authors suggest that low BNP levels could predispose to insulin resistance and affect lipid and fatty acid metabolism as well as increase inflammation. They also raise the possibility that metabolic traits should be taken into account when interpreting BNP levels. See p 1345.

	SIX-MONTH OUTCOME OF EMERGENCY PERCUTANEOUS CORONARY INTERVENTION IN RESUSCITATED PATIENTS AFTER CARDIAC ARREST COMPLICATING ST-ELEVATION MYOCARDIAL INFARCTION, by Garot et al.

 
The role of percutaneous coronary intervention in patients who are resuscitated from cardiac arrest following an acute ST-elevation myocardial infarction is unclear, and the outcome of these patients is poorly defined. The study by Garot et al retrospectively collected the data from 186 consecutive patients undergoing emergency percutaneous coronary intervention after resuscitated cardiac arrest complicating acute myocardial infarction from 5 centers. Most of the patients were resuscitated out of the hospital by mobile medical care units. Shock was present on admission in 52%. Percutaneous coronary intervention was successful in 87% of the patients. Six-month survival rate was 54%. The multivariable predictors of survival . . . [Full Text of this Article]

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