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(Circulation. 2007;115:2591.)
© 2007 American Heart Association, Inc.

Issue Highlights

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	RISK OF THROMBOEMBOLISM IN HEART FAILURE: AN ANALYSIS FROM THE SUDDEN CARDIAC DEATH IN HEART FAILURE TRIAL (SCD-HeFT), by Freudenberger et al.

 
In the current issue of Circulation, Freudenberger and colleagues evaluated the incidence of thromboembolism in patients with heart failure who did not have atrial fibrillation or a prosthetic heart valve. An analysis of 2144 patients who participated in the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) demonstrated that the risk of thromboembolism, including stroke, pulmonary embolization, or peripheral embolization, was approximately 1.7% per year, without antiarrhythmic therapy. In this cohort of patients with moderately stable symptomatic heart failure and an ejection fraction <0.35%, the incidence of clinical thromboembolism events was low and dependent on the level of left ventricular dysfunction at baseline. In addition, rates of thromboembolism were lower in patients randomized to amiodarone or implantable cardioverter-defibrillator devices compared to those randomized to placebo. Taken together, these data suggest that strategies for the prevention of thromboembolism in patients with heart failure may be possible. See p 2637.

	CASE VOLUME AND MORTALITY IN PEDIATRIC CARDIAC SURGERY PATIENTS IN CALIFORNIA, 1998–2003, by Bazzani and Marcin

 
Annual surgical case volume for congenital heart surgery has been reported to be inversely related to in-hospital mortality. Recent studies have suggested that the magnitude of association between mortality and case volume may be decreasing with time. Bazzani and Marcin reassess the hospital case volume–outcome relationship in California among pediatric cardiac surgery patients, using a more contemporary data set than previous investigations. Older models no longer predicted a consistent case volume–mortality relationship. Using a new model, increasing hospital volume was associated significantly with lower mortality, but this relationship was highly dependent upon the single institution in California performing >400 surgical . . . [Full Text of this Article]

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