Circulation. 2008;118:1519-1520
doi: 10.1161/CIRCULATIONAHA.108.191021
(Circulation. 2008;118:1519-1520.)
© 2008 American Heart Association, Inc.
Clinical Summaries
An extract of the first 250 words of the full text is provided, because this article has no abstract.
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Clinical Outcome After Surgical Correction of Mitral Regurgitation Due to Papillary Muscle Rupture
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Papillary muscle rupture (PMR) after myocardial infarction (MI)
is rare but deadly. Radical treatment for PMR is mitral valve
surgery, which is associated with high operative mortality.
PMR presentation is usually catastrophic, and diagnosis often
is difficult because the murmur is heard inconsistently. Long-term
outcome of surgery is uncertain because of the small sizes of
the published series. Thus, clinical management is difficult,
and surgical decisions may be tentative. To address these issues,
we examined the outcome of 54 patients who underwent post-MI
PMR surgery between 1980 and 2000 at our institution. We confirmed
the seriousness of PMR presentation with shock, pulmonary edema,
or cardiac arrest in 91%. Operative mortality was high but was
lower with coronary artery bypass graft and tended to decrease
in recent years, declining from 67% (before 1990 without coronary
artery bypass graft) to 8.7% (after 1990 with coronary artery
bypass graft). Another development was valve repair, feasible
in 41% after 1990, but its impact on outcome cannot be determined
because of the small sample. We compared the long-term outcome
of operative survivors with that of patients with similar MI
but without PMR who had survived the first 30 days after MI.
This comparison showed identical 5-year survival and similar
heart failure rates. Thus, our study, while emphasizing the
seriousness of PMR, is encouraging: Recent surgery is more often
reparative, has markedly improved operative risk with coronary
artery bypass graft, and results in restoration of long-term
life expectancy and morbidity to that of a similar but
. . . [Full Text of this Article]
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