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(Circulation. 2008;118:465-466.)
© 2008 American Heart Association, Inc.

Clinical Summaries

An extract of the first 250 words of the full text is provided, because this article has no abstract.

	Does Sodium Nitroprusside Decrease the Incidence of Atrial Fibrillation After Myocardial Revascularization? A Pilot Study

 
Postoperative atrial fibrillation (AF) is a frequent complication after coronary artery bypass grafting and is associated with increased morbidity and hospital stay. In this pilot study, we investigated whether sodium nitroprusside (SNP), a nitric oxide donor administered during surgery, can reduce the frequency of AF. We prospectively randomized 100 consecutive patients undergoing elective coronary artery bypass graft operations to a control group (dextrose 5% in water) and an SNP group (treated with SNP 0.5 µg · kg^–1 · min^–1 during the rewarming period). During the hospitalization, AF episodes were significantly reduced in the SNP group, and the duration of AF in the SNP group was significantly shorter than that in the control group. C-reactive protein levels were higher postoperatively in the control group than in the SNP group. Postoperative AF patients had a prolonged postoperative hospital stay. The present study shows that intraoperative treatment with SNP decreases postoperative AF. Whether this is mediated through an antiinflammatory mechanism of NO is unclear. These findings will require confirmation in a larger study. See p 476.

	Relation Between Body Mass Index, Waist Circumference, and Death After Acute Myocardial Infarction

 
The present study underscores the high prevalence of increased body mass index and waist circumference in patients with acute myocardial infarction, present in one quarter and one half of the patients, respectively. Until the epidemic progression of obesity is confronted, cardiologists will be faced with a growing prevalence of obesity in patients with acute myocardial infarction. Given this high prevalence, the characterization of cardiovascular risk associated with obesity after the index event is important. Most studies . . . [Full Text of this Article]

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