Circulation. 2008;118:697-698
doi: 10.1161/CIRCULATIONAHA.108.190521
(Circulation. 2008;118:697-698.)
© 2008 American Heart Association, Inc.
Clinical Summaries
An extract of the first 250 words of the full text is provided, because this article has no abstract.
|
 |
Routine Use of Bilateral Skeletonized Internal Thoracic Artery Grafting: Long-Term Results
|
|---|
Recent studies have shown survival benefit and freedom from
reintervention with the use of 2 internal thoracic arteries
(ITAs) compared with a single ITA. However, in most of these
studies, bilateral ITA (BITA) grafting is offered to only a
selected group of nonurgent, nondiabetic young patients. Unlike
those reports, our study describes long-term results of BITA
grafting in nonselected patients. The study includes many elderly,
emergency, and diabetic patients who would not otherwise be
referred for BITA grafting. In most centers, the ITA is isolated
from the chest wall as a pedicle, together with the vein, muscle,
fat, and accompanying endothoracic fascia. This technique damages
blood supply to the sternum, which in turn impedes sternal healing
and exposes the sternum to the risks of early dehiscence and
infection in operations involving both ITAs. The risk of sternal
infection is particularly high in patients with preoperatively
limited sternal blood supply such as the elderly and those with
diabetes mellitus. Harvesting the ITA as a skeletonized artery
preserves sternal collateral blood supply, thus enabling more
rapid healing and lower risk of infection. We have found that
skeletonized BITA grafting is associated with low morbidity
and good long-term results. Use of skeletonized BITA was found
to be an appropriate technique for the elderly and most patients
with diabetes mellitus. However, in patients with chronic lung
disease, in repeat operations, and in obese and female diabetic
patients, the risk of sternal infection is still unacceptably
high; for these patients, we advocate operations incorporating
only
. . . [Full Text of this Article]
Related Articles:
-
Genetic Ablation of the Bmpr2 Gene in Pulmonary Endothelium Is Sufficient to Predispose to Pulmonary Arterial Hypertension
- Kwon-Ho Hong, Young Jae Lee, Eunji Lee, Sung Ok Park, Chul Han, Hideyuki Beppu, En Li, Mohan K. Raizada, Kenneth D. Bloch, and S. Paul Oh
Circulation 2008 118: 722-730.
[Abstract]
[Full Text]
-
Heterogeneity of Left Ventricular Wall Thickening Mechanisms
- Allen Cheng, Tom C. Nguyen, Marcin Malinowski, George T. Daughters, D. Craig Miller, and Neil B. Ingels, Jr
Circulation 2008 118: 713-721.
[Abstract]
[Full Text]
-
Routine Use of Bilateral Skeletonized Internal Thoracic Artery Grafting: Long-Term Results
- D. Pevni, G. Uretzky, A. Mohr, R. Braunstein, A. Kramer, Y. Paz, I. Shapira, and R. Mohr
Circulation 2008 118: 705-712.
[Abstract]
[Full Text]
-
Suppression of c-Cbl Tyrosine Phosphorylation Inhibits Neointimal Formation in Balloon-Injured Rat Arteries
- Zhihui Tang, Ying Wang, Yanbo Fan, Yi Zhu, Shu Chien, and Nanping Wang
Circulation 2008 118: 764-772.
[Abstract]
[Full Text]
-
Apolipoprotein CIII Links Hyperlipidemia With Vascular Endothelial Cell Dysfunction
- Akio Kawakami, Mizuko Osaka, Mariko Tani, Hiroshi Azuma, Frank M. Sacks, Kentaro Shimokado, and Masayuki Yoshida
Circulation 2008 118: 731-742.
[Abstract]
[Full Text]
-
Antisense Oligonucleotide Directed to Human Apolipoprotein B-100 Reduces Lipoprotein(a) Levels and Oxidized Phospholipids on Human Apolipoprotein B-100 Particles in Lipoprotein(a) Transgenic Mice
- Esther Merki, Mark J. Graham, Adam E. Mullick, Elizabeth R. Miller, Rosanne M. Crooke, Robert E. Pitas, Joseph L. Witztum, and Sotirios Tsimikas
Circulation 2008 118: 743-753.
[Abstract]
[Full Text]
-
Reduced Atherosclerotic Lesions in P2Y1/Apolipoprotein E Double-Knockout Mice: The Contribution of Non–Hematopoietic-Derived P2Y1 Receptors
- Béatrice Hechler, Monique Freund, Catherine Ravanat, Stéphanie Magnenat, Jean-Pierre Cazenave, and Christian Gachet
Circulation 2008 118: 754-763.
[Abstract]
[Full Text]