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(Circulation. 1996;93:2088.)
© 1996 American Heart Association, Inc.

Articles

Recurrent Thrombosis of Bileaflet Prosthetic Valves

Rafael Hirsch, MD; Alejandro Soldky, MD

From the Heart Institute, Rabin Medical Center, Beilinson Campus, Petah-Tiqva, Israel.

Correspondence to Rafael Hirsch, MD, The Heart Institute, Rabin Medical Center, Beilinson Campus, Petah Tiqva 49100, Israel.

	Introduction

 
A 48-year-old man with rheumatic heart disease had aortic and mitral valve replacement with bileaflet Carbomedix valves. Two months later, he presented in shock with acute thrombosis of the mitral valve, which was replaced with another bileaflet valve in an emergency operation. Three months later, he complained of shortness of breath and was found on Doppler echocardiography to have impaired ventricular function and a calculated peak instantaneous gradient of 100 mm Hg through the prosthetic aortic valve. Fluoroscopy in the right anterior oblique projection (a, systolic frame; b, diastolic frame) showed an immobile anterior leaflet of the aortic prosthesis in a nearly closed position and restricted movement of the posterior leaflet. Systolic color-Doppler flow signal through the prosthetic valve in the horizontal-plane transesophageal echocardiogram (c and d) had an unusual semicircular shape, the blocked anterior leaflet remaining "colorless." There was also mild aortic regurgitation through the posterior leaflet (not shown). The patient declined thrombolytic therapy, and in an effort to prevent another operation, he was treated in the intensive care unit with heparin. A week later, repeated fluoroscopy showed almost normal motion of the previously stuck anterior leaflet but no change in the restricted posterior leaflet. Ventricular function improved, but the valve remained stenotic, and the patient underwent reoperation. The excised valve shows small but firmly adherent thrombi around the leaflet hinges bilaterally, on both the aortic (e) and ventricular (f) sides of the valve. No hypercoagulation disorder was identified, and the patient is now on a combination of warfarin, . . . [Full Text of this Article]