(Circulation. 1998;97:2372-2374.)
© 1998 American Heart Association, Inc.
Images in Cardiovascular Medicine |
Coronary Artery Ectasia and Systolic Flow Cessation in Hypertrophic Cardiomyopathy
Stephan Gielen, MD;
Ruth H. Strasser, MD;
Wolfgang Kübler, MD;
; Christlieb Haller, MD
From the Department of Internal Medicine III, University of Heidelberg,
Germany.
Correspondence to C. Haller, MD, Medizinische Klinik III, Universität Heidelberg, Bergheimer Str 58, 69115 Heidelberg, Germany. E-mail challer@krzmail.krz.uni-heidelberg.de
Case Report
A 24-year-old woman was evaluated for exertional dyspnea and chest
pain. Echocardiography showed marked apical, septal
(14 mm), and anterolateral (21 mm) hypertrophy
with normal inferior and posterior wall thickness (Figure 1
). The patient underwent right and left
heart catheterization, with coronary and
biventricular angiography. The cardiac index was 2.2 L
· min-1 · m-2.
The left ventricular pressure was 100/0 to 10 mm Hg,
without evidence of an intracavitary gradient. Right anterior oblique
ventriculography demonstrated a subtotal obliteration of the left
ventricular cavity during systole (Figure 2
). Simultaneous right and
left ventricular angiography revealed a massively thickened
interventricular septum (Figure 3
). Coronary angiography showed
no hemodynamically relevant fixed stenosis. The
striking finding was the dilation and pronounced tortuosity of the
coronary arteries, particularly the left anterior descending
arterial (LAD) system (Figure 4
, bottom), without signs of a coronary
artery-to-left ventricular fistula. The coronary perfusion
pattern of the LAD showed marked dynamic changes: the dye propagation
occurred only during ventricular diastole;
during systole, radiocontrast flow practically ceased, with apparent
obliteration of the vascular lumen. Figure 4
shows the left
coronary arterial system during the same cardiac
cycle: during systole, the LAD system is "squeezed empty" (Figure 4
, top), while the same vessels are rapidly filled during the
subsequent diastole (Figure 4
, bottom). The dynamic changes
of luminal diameter are illustrated quantitatively in Figure 5
. The caliber of a compressed and
noncompressed branch of the LAD (Figure 4
, top and bottom, arrows) . . . [Full Text of this Article]
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