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Circulation. 1998;97:2372-2374

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(Circulation. 1998;97:2372-2374.)
© 1998 American Heart Association, Inc.


Images in Cardiovascular Medicine

Coronary Artery Ectasia and Systolic Flow Cessation in Hypertrophic Cardiomyopathy

Stephan Gielen, MD; Ruth H. Strasser, MD; Wolfgang Kübler, MD; ; Christlieb Haller, MD

From the Department of Internal Medicine III, University of Heidelberg, Germany.

Correspondence to C. Haller, MD, Medizinische Klinik III, Universität Heidelberg, Bergheimer Str 58, 69115 Heidelberg, Germany. E-mail challer@krzmail.krz.uni-heidelberg.de

Case Report

A 24-year-old woman was evaluated for exertional dyspnea and chest pain. Echocardiography showed marked apical, septal (14 mm), and anterolateral (21 mm) hypertrophy with normal inferior and posterior wall thickness (Figure 1Down). The patient underwent right and left heart catheterization, with coronary and biventricular angiography. The cardiac index was 2.2 L · min-1 · m-2. The left ventricular pressure was 100/0 to 10 mm Hg, without evidence of an intracavitary gradient. Right anterior oblique ventriculography demonstrated a subtotal obliteration of the left ventricular cavity during systole (Figure 2Down). Simultaneous right and left ventricular angiography revealed a massively thickened interventricular septum (Figure 3Down). Coronary angiography showed no hemodynamically relevant fixed stenosis. The striking finding was the dilation and pronounced tortuosity of the coronary arteries, particularly the left anterior descending arterial (LAD) system (Figure 4Down, bottom), without signs of a coronary artery-to-left ventricular fistula. The coronary perfusion pattern of the LAD showed marked dynamic changes: the dye propagation occurred only during ventricular diastole; during systole, radiocontrast flow practically ceased, with apparent obliteration of the vascular lumen. Figure 4Down shows the left coronary arterial system during the same cardiac cycle: during systole, the LAD system is "squeezed empty" (Figure 4Down, top), while the same vessels are rapidly filled during the subsequent diastole (Figure 4Down, bottom). The dynamic changes of luminal diameter are illustrated quantitatively in Figure 5Down. The caliber of a compressed and noncompressed branch of the LAD (Figure 4Down, top and bottom, arrows) . . . [Full Text of this Article]




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