Correspondence to Ezra A. Amsterdam, MD, Division of Cardiovascular Medicine, University of California, Davis, 4150 V St, Suite 3500, Sacramento, CA 95817.
A 51-year-old man was admitted to an outside hospital for
weight gain, dyspnea on exertion, and orthopnea. He was found to have
bilateral pleural effusions, ascites, and marked peripheral
edema. An echocardiogram revealed normal right and left
ventricular systolic function. As a result of the
echocardiographic findings, congestive heart failure
(CHF) was given a low priority in the differential. Subsequently, an
extensive and comprehensive workup was undertaken, including
consultations by specialists in infectious disease, rheumatology,
oncology, surgical oncology, and pathology. With the goal of
discovering an occult malignancy, multiple tissues and fluids were
obtained and sent for pathological evaluation. These included pleural
and peritoneal fluid, cervical lymph nodes, pleural biopsy, biopsy of a
pelvic mass, and bladder biopsy. All biopsies, cultures, and serologies
were negative for neoplasia, infection, or vasculitis. The patient was
then referred to our institution for further evaluation.
History and physical examination were consistent with the
diagnosis of CHF. A Swan-Ganz catheter was placed for bedside
hemodynamic monitoring while aggressive
diuretic therapy was administered. Simultaneous
right and left heart catheterization demonstrated
equalization of elevated ventricular diastolic
pressures and normal systolic function. The right
ventricular pressure tracing was consistent with a
constrictive or restrictive process (Fig 1a
This article has been cited by other articles:
© 1998 American Heart Association, Inc.
Images in Cardiovascular Medicine
Constrictive Pericarditis
). Computerized tomography of the chest
demonstrated a thickened pericardium, which confirmed the diagnosis of
constrictive pericarditis (Fig 2
). The
patient was referred to cardiothoracic surgery for pericardiectomy.

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Figure 1. a, Initial bedside right
ventricular (RV) pressure tracing with
simultaneous electrocardiogram (EKG). Note
elevated RV diastolic pressure with characteristic
dip-and-plateau
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R. B. McCully, S. T. Higano, J. K. Oh, E. A. Amsterdam, and S. D. Correa
Diagnosis of Constrictive Pericarditis • Response
Circulation,
May 11, 1999;
99(18):
2476 - 2479.
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