Gene Therapy Ameliorates Cardiovascular Disease in Dogs With Mucopolysaccharidosis VII
Circulation Sleeper et al.
110: 815
Data Supplement
Color flow Doppler echocardiographic loops from right parasternum showing blood flow through mitral valve. Left atrium is on right and left ventricle is on left side of images. Red- and blue-labeled flow is normal, whereas flow labeled with a mosaic pattern (multiple colors) is consistent with high-velocity flow. In untreated affected individual (A), note mosaic color pattern in left atrium consistent with moderate MR. However, in normal (B), RV-treated (C), and HGV/RV-treated (D) individuals, there is no abnormal flow detected.
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