Overexpression of Wild-Type Heat Shock Protein 27 and a Nonphosphorylatable Heat Shock Protein 27 Mutant Protects Against Ischemia/Reperfusion Injury in a Transgenic Mouse Model
Circulation Hollander et al.
110: 3544
Data Supplement
Files in this Data Supplement:
- Data Supplement Figure
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(Microsoft PowerPoint) (33.5 kb). Contractile function of control, hsp27 transgenic (hsp27tg), and mutant hsp27 transgenic (mut-hsp27tg) animals after global ischemia (20 min) and reperfusion (1 hr) insult in Langendorff perfused hearts. (A) Developed pressure (DP) for hsp27tg, mut-hsp27tg, and control animals. *P<0.01 for hsp27tg and mut-hsp27tg vs control. (B) Peak systolic pressure (PSP) for hsp27tg, mut-hsp27tg, and control animals. *P<0.01 for mut-hsp27tg vs hsp27tg and control. (C) End diastolic pressure (EDP) for hsp27tg, mut-hsp27tg, and control animals. *P<0.01 for hsp27tg vs mut-hsp27tg and control. All values are represented as meanąSEM. N=10 for each group.
